Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.78 |
| ▸ | MEN1 | O00255 | 5/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.78 |
| ▸ | USP2 | O75604 | 1/20 | 0.78 |
| ▸ | CDK4 | P11802 | 1/20 | 0.78 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.78 |
| ▸ | CCND1 | P24385 | 1/20 | 0.78 |
| ▸ | MAPT | P10636 | 4/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.62 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.62 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.49 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL25366634 | 0.98 | ALDH1A1 (0.75) | ALDH1A1MEN1KMT2AUSP2CDK4 | |
| SCHEMBL29555396 | 0.89 | ALDH1A1 (0.68) | ALDH1A1MEN1KMT2AUSP2CDK4 | |
| SCHEMBL1450283 | 0.89 | ALDH1A1 (0.68) | ALDH1A1MEN1KMT2AUSP2CDK4 | |
| SCHEMBL7068245 | 0.89 | ALDH1A1 (0.72) | ALDH1A1MEN1KMT2AUSP2CDK4 | |
| SCHEMBL5660613 | 0.89 | ALDH1A1 (0.62) | ALDH1A1MEN1KMT2AUSP2CDK4 | |
| SCHEMBL7940135 | 0.88 | ALDH1A1 (1.00) | ALDH1A1MEN1KMT2AUSP2CDK4 | |
| Hydrochloric Acid SCHEMBL19149285 | 0.87 | ALDH1A1 (0.70) | ALDH1A1MEN1KMT2AUSP2CDK4 | |
| SCHEMBL9470338 | 0.86 | ALDH1A1 (0.68) | ALDH1A1MEN1KMT2AUSP2CDK4 | |
| SCHEMBL1027312 | 0.84 | ALDH1A1 (0.70) | ALDH1A1MEN1KMT2AUSP2CDK4 | |
| SCHEMBL7213519 | 0.81 | ALDH1A1 (0.78) | ALDH1A1MEN1KMT2AUSP2CDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240360113-A1 | AMINOARYL-INTEGRIN AGONISTS COMPOUNDS | TEXAS HEART INSTITUTE (US) | 2024-10-31 | — | — | US | disclosed |
| EP-4384516-A1 | AMINOARYL-INTEGRIN AGONISTS COMPOUNDS | Texas Heart Institute (US) | 2024-06-19 | — | — | EP | disclosed |
| CN-117916237-A | Amino aryl integrin agonist compounds | 德克萨斯心脏研究所 | 2024-04-19 | — | — | CN | disclosed |
| WO-2023018472-A9 | AMINOARYL-INTEGRIN AGONISTS COMPOUNDS | TEXAS HEART INSTITUTE (US) | 2023-07-13 | — | — | WO | disclosed |
| WO-2023018472-A1 | AMINOARYL-INTEGRIN AGONISTS COMPOUNDS | TEXAS HEART INSTITUTE (US) | 2023-02-16 | — | — | WO | disclosed |
| US-20210169850-A1 | INDOLINE DERIVATIVES, COMPOSITIONS COMPRISING THEM AND USES THEREOF | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) | 2021-06-10 | — | — | US | disclosed |
| US-9850203-B2 | Autotaxin inhibitor compounds | PHARMAKEA, INC. (US) | 2017-12-26 | — | — | US | disclosed |
| EP-3049405-A1 | AUTOTAXIN INHIBITOR COMPOUNDS | Pharmakea Inc. (US) | 2016-08-03 | — | — | EP | disclosed |
| US-20160214935-A1 | AUTOTAXIN INHIBITOR COMPOUNDS | DF 2024 IP ACQUISITION, LLC | 2016-07-28 | — | — | US | disclosed |
| WO-2015048301-A1 | AUTOTAXIN INHIBITOR COMPOUNDS | PHARMAKEA, INC. (US) | 2015-04-02 | — | — | WO | disclosed |
| CN-1118781-A | Heterocyclic compound with activity against diabetes and preparation and application of same | MITSUTAKA CO LTD (JP) | 1996-03-20 | — | — | CN | disclosed |
| EP-0676398-A2 | Heterocyclic compounds having anti-diabetic activity, their preparation and their use | SANKYO COMPANY LIMITED (JP) | 1995-10-11 | — | — | EP | disclosed |
| WO-1995014666-A1 | INDOLYL GROUP CONTAINING COMPOUNDS AND THE USE THEREOF TO PROMOTE THE RELEASE OF GROWTH HORMONE(S) | MERCK & CO., INC. (US) | 1995-06-01 | — | — | WO | disclosed |
| US-5202938-A | Laminated waveguiding polarizer utilizing polymeric birefringent cladding | HOECHST CELANESE CORP. (US) | 1993-04-13 | — | — | US | disclosed |
| US-5186865-A | Aminoazobenzene derivatives and polymers | ALLIED-SIGNAL INC. (US) | 1993-02-16 | — | — | US | disclosed |
| US-5171803-A | Copolymer with side chains exhibiting nonlinear optical response | HOECHST CELANESE CORP. | 1992-12-15 | — | — | US | disclosed |
| US-5061404-A | WAVEGUIDES | ALLIED-SIGNAL INC. (US) | 1991-10-29 | — | — | US | disclosed |
| US-5036142-A | Reaction of diazonium salt with addition polymer containing aminophenyl group | ALLIED-SIGNAL INC. (US) | 1991-07-30 | — | — | US | disclosed |
| WO-1991009842-A1 | ELECTRO-OPTICAL MATERIALS AND LIGHT MODULATOR DEVICES CONTAINING SAME | ALLIED-SIGNAL INC. (US) | 1991-07-11 | — | — | WO | disclosed |
| WO-1991009885-A2 | PROCESS FOR MAKING ELECTRO-OPTICALLY ACTIVE POLYMERS | ALLIED-SIGNAL INC. (US) | 1991-07-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210169850-A1 | INDOLINE DERIVATIVES, COMPOSITIONS COMPRISING THEM AND USES THEREOF | IDO1, IDO2, INMT | ALDH1A1 1952/4885MEN1 4005/4885KMT2A 4235/4885 |
| US-20160214935-A1 | AUTOTAXIN INHIBITOR COMPOUNDS | ENPP2, SERPINB1, SERPINE1 | ALDH1A1 4720/4885MEN1 737/4885KMT2A 2780/4885 |
| US-20240360113-A1 | AMINOARYL-INTEGRIN AGONISTS COMPOUNDS | ITGB3, ITGA2, ITGAV | ALDH1A1 1217/4885MEN1 4571/4885KMT2A 2230/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.