Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 15/20 | 0.46 |
| ▸ | PPARG | P37231 | 14/20 | 0.46 |
| ▸ | RARG | P13631 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NR5A2 | O00482 | 1/20 | 0.36 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.36 |
| ▸ | RARA | P10276 | 3/20 | 0.35 |
| ▸ | RARB | P10826 | 3/20 | 0.35 |
| ▸ | RXRB | P28702 | 3/20 | 0.35 |
| ▸ | RXRG | P48443 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7942623 | 0.87 | KMT2A (0.38) | RXRAPPARGRARGKMT2AKDM4E | |
| SCHEMBL7943266 | 0.86 | RXRA (0.50) | RXRAPPARGRARGKMT2ANR5A2 | |
| SCHEMBL7941341 | 0.86 | ALDH1A1 (0.37) | RXRAPPARGRARGKMT2AKDM4E | |
| SCHEMBL7941411 | 0.83 | NR5A2 (0.49) | RXRAPPARGRARGNR5A2NR5A1 | |
| SCHEMBL5664156 | 0.82 | RXRA (0.52) | RXRAPPARGRARGNR5A2NR5A1 | |
| SCHEMBL7944853 | 0.80 | TNFRSF1A (0.45) | KMT2AKDM4EALDH1A1TSHR | |
| SCHEMBL7943067 | 0.79 | NR1H4 (0.48) | KMT2AKDM4EALDH1A1HSD17B10TSHR | |
| SCHEMBL8434295 | 0.78 | RXRA (0.37) | RXRAPPARGRARGALDH1A1TSHR | |
| SCHEMBL2772372 | 0.77 | RXRA (0.56) | RXRAPPARGRARGNR5A2NR5A1 | |
| SCHEMBL5665923 | 0.77 | RXRA (0.56) | RXRAPPARGRARGNR5A2NR5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242514-B1 | CYCLIC PHOSPHATE OR PHOSPHONATE; HEAT AND OXIDATION STABILIZER ESPECIALLY FOR OLEFIN POLYMERS AND ENGINEERING THERMOPLASTICS | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 2001-06-05 | — | — | US | disclosed |
| US-5914361-A | IMPART HEAT STABILITY TO ORGANIC MATERIALS, INCLUDING POLYOLEFINS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-06-22 | — | — | US | disclosed |
| US-5891939-A | POLYMER STABILIZERS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-04-06 | — | — | US | disclosed |