Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 6/20 | 0.47 |
| ▸ | GSR | P00390 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 5/20 | 0.44 |
| ▸ | CA9 | Q16790 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MPO | P05164 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7944926 | 0.95 | CA2 (0.46) | CA2GSRCA12CA9KDM4E | |
| SCHEMBL7943010 | 0.91 | GSR (0.55) | CA2GSRCA12CA9KDM4E | |
| SCHEMBL15512896 | 0.85 | CA2 (0.59) | CA2GSRCA12TSHRSCN2A | |
| SCHEMBL6567771 | 0.79 | CA2 (0.55) | CA2KDM4ETSHRGABRA1GABRB2 | |
| SCHEMBL7933726 | 0.78 | HSPA5 (0.57) | CA2GSRKDM4ETSHRHSD17B10 | |
| SCHEMBL7943209 | 0.78 | GSR (0.51) | GSRKDM4ETSHRSCN2AALDH1A1 | |
| SCHEMBL6567369 | 0.78 | CA2 (0.53) | CA2TSHRGABRA1GABRB2ATM | |
| SCHEMBL6568673 | 0.76 | CA2 (0.52) | CA2KDM4ETSHRGABRA1GABRB2 | |
| SCHEMBL6568762 | 0.76 | CA2 (0.52) | CA2KDM4ETSHRGABRA1GABRB2 | |
| SCHEMBL7933754 | 0.75 | GAA (0.46) | CA2KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242514-B1 | CYCLIC PHOSPHATE OR PHOSPHONATE; HEAT AND OXIDATION STABILIZER ESPECIALLY FOR OLEFIN POLYMERS AND ENGINEERING THERMOPLASTICS | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 2001-06-05 | — | — | US | disclosed |
| US-5914361-A | IMPART HEAT STABILITY TO ORGANIC MATERIALS, INCLUDING POLYOLEFINS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-06-22 | — | — | US | disclosed |