Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 2/20 | 0.55 |
| ▸ | CA2 | P00918 | 6/20 | 0.50 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | CA12 | O43570 | 5/20 | 0.41 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | MPO | P05164 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7940433 | 0.91 | CA2 (0.47) | GSRCA2GABRA1GABRB2ALDH1A1 | |
| SCHEMBL7944926 | 0.89 | CA2 (0.46) | GSRCA2GABRA1GABRB2ALDH1A1 | |
| SCHEMBL15512896 | 0.88 | CA2 (0.59) | GSRCA2GABRA1GABRB2ALDH1A1 | |
| SCHEMBL7940282 | 0.80 | ALDH1A1 (0.51) | GSRALDH1A1KDM4EL3MBTL1PDCD1 | |
| SCHEMBL3809080 | 0.78 | CA2 (0.59) | GSRCA2GABRA1GABRB2ALDH1A1 | |
| SCHEMBL10706992 | 0.77 | CA2 (0.64) | CA2GABRA1GABRB2ALDH1A1ATM | |
| SCHEMBL7933905 | 0.76 | GSR (0.62) | GSRCA2ALDH1A1ATMKDM4E | |
| SCHEMBL7942924 | 0.76 | GSR (0.62) | GSRCA2ALDH1A1ATMKDM4E | |
| SCHEMBL15936550 | 0.76 | CA2 (0.44) | CA2GABRA1GABRB2ALDH1A1ATM | |
| SCHEMBL15936557 | 0.76 | CA2 (0.44) | CA2GABRA1GABRB2ALDH1A1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242514-B1 | CYCLIC PHOSPHATE OR PHOSPHONATE; HEAT AND OXIDATION STABILIZER ESPECIALLY FOR OLEFIN POLYMERS AND ENGINEERING THERMOPLASTICS | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 2001-06-05 | — | — | US | disclosed |
| US-5914361-A | IMPART HEAT STABILITY TO ORGANIC MATERIALS, INCLUDING POLYOLEFINS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-06-22 | — | — | US | disclosed |