Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15367945 | 0.90 | THRB (0.43) | TSHRTHRBALDH1A1CYP2D6CYP2C19 | |
| SCHEMBL2101100 | 0.83 | TSHR (0.45) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL19506931 | 0.82 | TSHR (0.44) | TSHRTHRBALDH1A1POLBAPEX1 | |
| Succinic Acid SCHEMBL28095171 | 0.81 | THRB (0.39) | TSHRTHRBALDH1A1CYP2D6CYP2C19 | |
| SCHEMBL14368857 | 0.81 | THRB (0.39) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL396824 | 0.80 | TSHR (0.50) | TSHRTHRBALDH1A1CYP2C19POLB | |
| SCHEMBL15337 | 0.80 | TSHR (0.50) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL51592 | 0.80 | TSHR (0.50) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL18492454 | 0.80 | THRB (0.48) | TSHRTHRBALDH1A1CYP2D6CYP2C19 | |
| Methacrylic Acid SCHEMBL3685758 | 0.79 | TSHR (0.45) | TSHRTHRBALDH1A1POLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105524285-B | Dendritic macromole containing thiocarbamide and dissaving polymer containing thiocarbamide and its preparation method and application | 浙江大学 | 2018-06-15 | — | — | CN | disclosed |
| US-20170306101-A1 | THIOUREA-CONTAINING DENDRIMER AND THIOUREA-CONTAINING HYPERBRANCHED POLYMER AS WELL AS PREPARATION METHODS THEREOF AND APPLICATIONS THEREOF | ZHEJIANG UNIVERSITY (CN) | 2017-10-26 | — | — | US | disclosed |
| US-20170306101-A1 | THIOUREA-CONTAINING DENDRIMER AND THIOUREA-CONTAINING HYPERBRANCHED POLYMER AS WELL AS PREPARATION METHODS THEREOF AND APPLICATIONS THEREOF | ZHEJIANG UNIVERSITY (CN) | 2017-10-26 | — | — | US | disclosed |
| CN-105524285-A | Thiourea-containing dendritic polymer and thiourea-containing hyperbranched polymer, preparation method and application thereof | UNIV ZHEJIANG | 2016-04-27 | — | — | CN | disclosed |
| EP-0863128-B1 | FLUORINATED POLYFUNCTIONAL (METH)ACRYLATE ESTERS, COMPOSITIONS, LOW-REFRACTION MATERIALS, AND ANTIREFLECTION FILMS | NOF CORP (JP) | 2001-11-21 | — | — | EP | disclosed |