SCHEMBL7940607

SCHEMBL7940607

Fc1ccc(SC(F)(F)F)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.61
KDM4E B2RXH2 1/20 0.61
TDP1 Q9NUW8 1/20 0.61
PTPRZ1 P23471 4/20 0.52
PTPN1 P18031 2/20 0.52
KCNK2 O95069 2/20 0.42
LMNA P02545 2/20 0.41
KIF11 P52732 1/20 0.41
HTT P42858 1/20 0.41
PPARG P37231 1/20 0.37
TRPV1 Q8NER1 1/20 0.37
SMN1; SMN2 Q16637 2/20 0.36
KCNH2 Q12809 1/20 0.36
KCNK10 P57789 1/20 0.36
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
MAPT P10636 1/20 0.35
ATM Q13315 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11106674 0.83 KCNK2 (0.51) ALDH1A1KDM4ETDP1PTPRZ1KCNK2
SCHEMBL23060729 0.79 ALDH1A1 (0.39) ALDH1A1KDM4ETDP1PTPRZ1PTPN1
SCHEMBL9489522 0.79 ALDH1A1 (0.39) ALDH1A1KDM4ETDP1PTPRZ1PTPN1
SCHEMBL10602187 0.79 ALDH1A1 (0.39) ALDH1A1KDM4ETDP1PTPRZ1PTPN1
SCHEMBL10978325 0.78 ALDH1A1 (0.61) ALDH1A1KDM4ETDP1PTPRZ1PTPN1
SCHEMBL9487742 0.77 ALDH1A1 (0.38) ALDH1A1KDM4ETDP1PTPRZ1PTPN1
SCHEMBL3989851 0.77 KDM4E (0.38) ALDH1A1KDM4ETDP1PTPRZ1PTPN1
SCHEMBL518851 0.76 ALDH1A1 (0.58) ALDH1A1KDM4ETDP1PTPRZ1PTPN1
SCHEMBL10935258 0.76 ALDH1A1 (0.58) ALDH1A1KDM4ETDP1PTPRZ1PTPN1
SCHEMBL7014603 0.76 ALDH1A1 (0.58) ALDH1A1KDM4ETDP1PTPRZ1PTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021011722-A1 MOLECULES HAVING CERTAIN PESTICIDAL UTILITIES, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES RELATED THERETO DOW AGROSCIENCES LLC (US) 2021-01-21 WO disclosed
US-6242654-B1 REACTING A PHENOLATE COMPOUND WITH AN ORGANIC FLUORINATING AGENT TO PREPARE A FLUORINE SUBSTITUTED AROMATIC COMPOUND MITSUI CHEMICALS, INC. (JP) 2001-06-05 US disclosed
EP-1013629-A1 Preparation process of fluorine subsituted aromatic compound Mitsui Chemicals, Inc. (JP) 2000-06-28 EP disclosed