Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | PTPRZ1 | P23471 | 4/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.50 |
| ▸ | KCNK2 | O95069 | 4/20 | 0.45 |
| ▸ | KCNK10 | P57789 | 4/20 | 0.45 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1260200 | 0.80 | CYP2A6 (0.38) | ALDH1A1KDM4ETDP1PTPRZ1PTPN1 | |
| SCHEMBL1230237 | 0.80 | CYP2A6 (0.38) | ALDH1A1KDM4ETDP1PTPRZ1PTPN1 | |
| SCHEMBL9185266 | 0.79 | ALDH1A1 (0.58) | ALDH1A1KDM4ETDP1PTPRZ1PTPN1 | |
| SCHEMBL25118403 | 0.77 | KDM4E (0.35) | ALDH1A1KDM4ETDP1PTPRZ1PTPN1 | |
| SCHEMBL10978325 | 0.76 | ALDH1A1 (0.61) | ALDH1A1KDM4ETDP1PTPRZ1PTPN1 | |
| SCHEMBL7940607 | 0.76 | ALDH1A1 (0.61) | ALDH1A1KDM4ETDP1PTPRZ1PTPN1 | |
| SCHEMBL27761242 | 0.75 | ALDH1A1 (0.54) | ALDH1A1KDM4ETDP1PTPRZ1PTPN1 | |
| SCHEMBL28535824 | 0.75 | ALDH1A1 (0.40) | ALDH1A1KDM4ETDP1PTPRZ1PTPN1 | |
| SCHEMBL6933019 | 0.74 | CYP2A6 (0.42) | ALDH1A1KDM4ETDP1CYP2A6MAOA | |
| SCHEMBL10935258 | 0.74 | ALDH1A1 (0.58) | ALDH1A1KDM4ETDP1PTPRZ1PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 251 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118652677-A | Preparation method and application of trifluoro methanesulfonyl end group diphenyl acetylene fluorescent liquid crystal composite material with controllable three-fold thermochromic property | 华南师范大学 | 2024-09-17 | — | — | CN | claimed |
| CN-101250144-A | Preparation method of 4-trifluoro-methylthio benzoic acid | JINTAN LINGYUN CHEMICAL INDUST (CN) | 2008-08-27 | — | — | CN | claimed |
| US-20250353828-A1 | SUBSTITUTED BIARYL ENDOCHIN-LIKE QUINOLONES WITH ENHANCED ANTIPARASITIC ACTIVITY | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2025-11-20 | — | — | US | disclosed |
| CN-119894869-A | Substituted biaryl kadetoxin-like quinolones having enhanced antiparasitic activity | 俄勒冈健康与科学大学 | 2025-04-25 | — | — | CN | disclosed |
| EP-4536639-A1 | SUBSTITUTED BIARYL ENDOCHIN-LIKE QUINOLONES WITH ENHANCED ANTIPARASITIC ACTIVITY | Oregon Health & Science University (US) | 2025-04-16 | — | — | EP | disclosed |
| US-20250099448-A1 | HETEROCYCLIC COMPOUNDS | HOFFMANN-LA ROCHE INC. (US) | 2025-03-27 | — | — | US | disclosed |
| EP-4469446-A1 | NEW HETEROCYCLIC COMPOUNDS | F. Hoffmann-La Roche AG (CH) | 2024-12-04 | — | — | EP | disclosed |
| CN-118652677-A | Preparation method and application of trifluoro methanesulfonyl end group diphenyl acetylene fluorescent liquid crystal composite material with controllable three-fold thermochromic property | 华南师范大学 | 2024-09-17 | — | — | CN | disclosed |
| US-20240151993-A1 | ELECTRON WITHDRAWING GROUP (EWG)-CONTAINING ORGANIC MOLECULES FOR IMPROVED OPTICAL PROPERTIES IN AR/VR COMPONENTS | META PLATFORMS TECHNOLOGIES, LLC | 2024-05-09 | — | — | US | disclosed |
| US-20240132470-A1 | Antibacterial Compounds | JANSSEN SCIENCES IRELAND UNLIMITED CO (IE) | 2024-04-25 | — | — | US | disclosed |
| WO-2024067560-A1 | SULFONAMIDE COMPOUND AND MEDICAL USE THEREOF | 中国药科大学 | 2024-04-04 | — | — | WO | disclosed |
| US-5107026-A | Fluorinated acetylene-containing aromatic amines and diamines | NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) | 1992-04-21 | — | — | US | disclosed |
| CN-1036562-A | To propanamine derivatives or improve one's methods relevant with propanamine derivatives | LILLY CO ELI (US) | 1989-10-25 | — | — | CN | disclosed |
| US-4575571-A | HALOGEN IN LIQUID HYDROGEN FLUORIDE | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1986-03-11 | — | — | US | disclosed |
| US-4552984-A | SULFONYLATION IN PRESENCE OF BORON TRIFLUORIDE, HYDROGEN FLUORIDE | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1985-11-12 | — | — | US | disclosed |
| EP-0092627-B1 | PROCESS FOR THE PREPARATION OF DI- OR TRIFLUOROMETHOXYPHENYL KETONES OR OF DI- OR TRIFLUOROMETHYLTHIOPHENYL KETONES | RHONE-POULENC CHIMIE (FR) | 1985-05-29 | — | — | EP | disclosed |
| EP-0085265-B1 | PROCESS FOR THE PREPARATION OF ALPHA,ALPHA-DIFLUOROALKOXY OR ALPHA,ALPHA-DIFLUOROALKYLTHIOPHENYL KETONES | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1985-05-22 | — | — | EP | disclosed |
| EP-0084743-B1 | PROCESS FOR THE PREPARATION OF ALPHA, ALPHA-DIFLUOROALKOXY OR ALPHA, ALPHADIFLUOROALKYLTHIOPHENYL SULFONES | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1984-11-21 | — | — | EP | disclosed |
| US-4446078-A | REACTING A POLYHALOALKOXY- OR POLYHALOALKYLTHIOBENZENE WITH A CARBOXYLIC DERIVATIVE, BORON TRIFLUORIDE | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1984-05-01 | — | — | US | disclosed |
| US-4438043-A | Process for preparation of di- or trifluoromethoxyphenyl ketones or di- or trifluoromethylthiophenyl ketones | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1984-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250353828-A1 | SUBSTITUTED BIARYL ENDOCHIN-LIKE QUINOLONES WITH ENHANCED ANTIPARASITIC ACTIVITY | EPX, TFEB, EPHX1 | ALDH1A1 2498/4885KDM4E 2282/4885TDP1 4356/4885 |
| US-20240151993-A1 | ELECTRON WITHDRAWING GROUP (EWG)-CONTAINING ORGANIC MOLECULES FOR IMPROVED OPTICAL PROPERTIES IN AR/VR COMPONENTS | AR, OR10J3, ESRRG | ALDH1A1 2350/4885KDM4E 861/4885TDP1 4124/4885 |
| US-20250099448-A1 | HETEROCYCLIC COMPOUNDS | OPRM1, CYP1A1, CYP3A4 | ALDH1A1 411/4885KDM4E 1137/4885TDP1 2538/4885 |
| US-20240132470-A1 | Antibacterial Compounds | FDPS, SQOR, NDUFS3 | ALDH1A1 1869/4885KDM4E 3387/4885TDP1 3265/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.