Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | ALPG | P10696 | 1/20 | 0.51 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.46 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7716847 | 0.93 | LTA4H (0.53) | HPGDLMNASMN1; SMN2ALPGSRD5A2 | |
| SCHEMBL11420172 | 0.91 | ALDH1A1 (0.61) | HPGDLMNASRD5A2ALDH1A1ELANE | |
| SCHEMBL27483853 | 0.84 | ALDH1A1 (0.70) | HPGDLMNASMN1; SMN2ALPGSRD5A2 | |
| Benzene SCHEMBL27709388 | 0.84 | ALDH1A1 (0.70) | HPGDLMNASMN1; SMN2ALPGSRD5A2 | |
| SCHEMBL17068941 | 0.84 | ALDH1A1 (0.70) | HPGDLMNASMN1; SMN2ALPGSRD5A2 | |
| SCHEMBL251921 | 0.84 | ALDH1A1 (0.70) | HPGDLMNASMN1; SMN2ALPGSRD5A2 | |
| SCHEMBL7940606 | 0.84 | ALDH1A1 (0.70) | HPGDLMNASMN1; SMN2ALPGSRD5A2 | |
| SCHEMBL7938401 | 0.84 | ESR1 (0.68) | HPGDLMNASRD5A2ALDH1A1HTT | |
| SCHEMBL7373156 | 0.82 | ALDH1A1 (0.67) | HPGDLMNASMN1; SMN2ALPGSRD5A2 | |
| SCHEMBL13978732 | 0.82 | POLB (0.44) | LMNASMN1; SMN2SRD5A2ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242654-B1 | REACTING A PHENOLATE COMPOUND WITH AN ORGANIC FLUORINATING AGENT TO PREPARE A FLUORINE SUBSTITUTED AROMATIC COMPOUND | MITSUI CHEMICALS, INC. (JP) | 2001-06-05 | — | — | US | disclosed |
| EP-1013629-A1 | Preparation process of fluorine subsituted aromatic compound | Mitsui Chemicals, Inc. (JP) | 2000-06-28 | — | — | EP | disclosed |