Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 3/20 | 0.50 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19680580 | 0.90 | ALOX15 (0.50) | ALOX15NFE2L2ALDH1A1NPC1MAPT | |
| SCHEMBL17861084 | 0.90 | ALOX15 (0.50) | ALOX15NFE2L2ALDH1A1NPC1MAPT | |
| SCHEMBL17861078 | 0.90 | ALOX15 (0.50) | ALOX15NFE2L2ALDH1A1NPC1MAPT | |
| SCHEMBL19680576 | 0.88 | ALOX15 (0.51) | ALOX15NFE2L2ALDH1A1NPC1MAPT | |
| SCHEMBL17861023 | 0.88 | ALOX15 (0.51) | ALOX15NFE2L2ALDH1A1NPC1MAPT | |
| SCHEMBL17861077 | 0.88 | ALOX15 (0.51) | ALOX15NFE2L2ALDH1A1NPC1MAPT | |
| SCHEMBL7940736 | 0.88 | ALOX15 (0.48) | ALOX15NFE2L2ALDH1A1MAPTESR2 | |
| SCHEMBL7940744 | 0.82 | ALOX15 (0.45) | ALOX15NFE2L2ALDH1A1NPC1MAPT | |
| SCHEMBL14392245 | 0.82 | ALOX15 (0.60) | ALOX15ALDH1A1NPC1MAPTRAB9A | |
| SCHEMBL2482660 | 0.81 | ALOX15 (0.47) | ALOX15NFE2L2ALDH1A1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6258854-B1 | KETONE ETHERS FOR ODORS | GIVAUDAN ROURE ( INTERNATIONAL ) SA (CH) | 2001-07-10 | — | — | US | disclosed |
| EP-0983990-A2 | Ketones useful as precursors for organoleptic compounds | Givaudan Roure (International) S.A. (CH) | 2000-03-08 | — | — | EP | disclosed |