Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 13/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.38 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.38 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.37 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.37 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.37 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.37 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7939772 | 1.00 | CCR5 (0.54) | CCR5LMNAGAAHSD17B2KDM4E | |
| SCHEMBL7941215 | 1.00 | CCR5 (0.54) | CCR5LMNAGAAHSD17B2KDM4E | |
| SCHEMBL7497787 | 1.00 | CCR5 (0.54) | CCR5LMNAGAAHSD17B2KDM4E | |
| SCHEMBL7940905 | 1.00 | CCR5 (0.54) | CCR5LMNAGAAHSD17B2KDM4E | |
| SCHEMBL7488769 | 0.83 | CCR5 (0.41) | CCR5CACNA1C | |
| SCHEMBL7973519 | 0.83 | CCR5 (0.41) | CCR5CACNA1C | |
| SCHEMBL7973894 | 0.83 | CCR5 (0.41) | CCR5CACNA1C | |
| SCHEMBL7491806 | 0.81 | CCR5 (0.54) | CCR5 | |
| SCHEMBL7972491 | 0.81 | CCR5 (0.54) | CCR5 | |
| SCHEMBL7972489 | 0.81 | CCR5 (0.54) | CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6248755-B1 | ANTIINFLAMMATORY AGENTS; ANTIALLERGENS; AUTOIMMUNE DISEASES | MERCK & CO., INC. | 2001-06-19 | — | — | US | disclosed |