Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 8/20 | 0.41 |
| ▸ | NMT1 | P30419 | 2/20 | 0.38 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.36 |
| ▸ | CACNB1 | Q02641 | 2/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.36 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.36 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7973519 | 1.00 | CCR5 (0.41) | CCR5NMT1CACNA2D1CACNA1BCACNB1 | |
| SCHEMBL7488769 | 1.00 | CCR5 (0.41) | CCR5NMT1CACNA2D1CACNA1BCACNB1 | |
| SCHEMBL7939772 | 0.83 | CCR5 (0.54) | CCR5CACNA1C | |
| SCHEMBL7941215 | 0.83 | CCR5 (0.54) | CCR5CACNA1C | |
| SCHEMBL7497787 | 0.83 | CCR5 (0.54) | CCR5CACNA1C | |
| SCHEMBL7940905 | 0.83 | CCR5 (0.54) | CCR5CACNA1C | |
| SCHEMBL7941000 | 0.83 | CCR5 (0.54) | CCR5CACNA1C | |
| SCHEMBL7986574 | 0.80 | MEN1 (0.36) | CCR5CACNA2D1CACNA1BCACNB1OPRM1 | |
| SCHEMBL7972727 | 0.80 | MEN1 (0.36) | CCR5CACNA2D1CACNA1BCACNB1OPRM1 | |
| SCHEMBL7497904 | 0.80 | MEN1 (0.36) | CCR5CACNA2D1CACNA1BCACNB1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265434-B1 | ANTIINFLAMMATORY AGENTS | MERCK & CO., INC. | 2001-07-24 | — | — | US | disclosed |