Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | P4HTM | Q9NXG6 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7356681 | 0.85 | MAPK1 (0.75) | MAPK1L3MBTL1KDM4ENPC1RAB9A | |
| SCHEMBL1004608 | 0.81 | MAPK1 (0.64) | MAPK1L3MBTL1KDM4EP4HTMNPC1 | |
| SCHEMBL29508473 | 0.78 | MAPK1 (1.00) | MAPK1L3MBTL1KDM4EP4HTMNPC1 | |
| SCHEMBL69747 | 0.78 | MAPK1 (1.00) | MAPK1L3MBTL1KDM4EP4HTMNPC1 | |
| SCHEMBL29637478 | 0.77 | MAPK1 (0.61) | MAPK1L3MBTL1KDM4ENPC1RAB9A | |
| SCHEMBL1971939 | 0.77 | MAPK1 (0.61) | MAPK1L3MBTL1KDM4ENPC1RAB9A | |
| SCHEMBL24775612 | 0.75 | MAPK1 (0.64) | MAPK1L3MBTL1KDM4EP4HTMNPC1 | |
| SCHEMBL989398 | 0.75 | MAPK1 (0.79) | MAPK1L3MBTL1KDM4EP4HTMCA12 | |
| SCHEMBL64024 | 0.75 | MAPK1 (0.79) | MAPK1L3MBTL1KDM4EP4HTMMAPT | |
| SCHEMBL29826109 | 0.75 | MAPK1 (0.79) | MAPK1L3MBTL1KDM4EP4HTMMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010017079-A1 | OXAZOLE DERIVATIVES USEFUL AS INHIBITORS OF FAAH | MERCK & CO., INC. (US) | 2010-02-11 | — | — | WO | disclosed |