Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.79 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.74 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.74 |
| ▸ | P4HTM | Q9NXG6 | 6/20 | 0.66 |
| ▸ | P4HA1 | P13674 | 2/20 | 0.66 |
| ▸ | MIF | P14174 | 1/20 | 0.66 |
| ▸ | HCAR3 | P49019 | 5/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | GABRP | O00591 | 1/20 | 0.48 |
| ▸ | GABRD | O14764 | 1/20 | 0.48 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.48 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.48 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.48 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.48 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.48 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.48 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.48 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.48 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.48 |
| ▸ | GABRE | P78334 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29826109 | 1.00 | MAPK1 (0.79) | MAPK1KDM4EL3MBTL1P4HTMP4HA1 | |
| SCHEMBL69747 | 0.89 | MAPK1 (1.00) | MAPK1KDM4EL3MBTL1P4HTMP4HA1 | |
| SCHEMBL29508473 | 0.89 | MAPK1 (1.00) | MAPK1KDM4EL3MBTL1P4HTMP4HA1 | |
| SCHEMBL28630848 | 0.87 | MAPK1 (0.60) | MAPK1KDM4EL3MBTL1P4HTMP4HA1 | |
| SCHEMBL64700 | 0.85 | MAPK1 (1.00) | MAPK1KDM4EL3MBTL1P4HTMP4HA1 | |
| SCHEMBL989398 | 0.85 | MAPK1 (0.79) | MAPK1KDM4EL3MBTL1P4HTMP4HA1 | |
| SCHEMBL21173949 | 0.85 | P4HTM (0.70) | MAPK1KDM4EL3MBTL1P4HTMP4HA1 | |
| SCHEMBL8251331 | 0.84 | MAPK1 (0.77) | MAPK1KDM4EL3MBTL1P4HTMP4HA1 | |
| SCHEMBL1019173 | 0.84 | MAPK1 (0.77) | MAPK1KDM4EL3MBTL1P4HTMP4HA1 | |
| SCHEMBL30401004 | 0.84 | MAPK1 (0.77) | MAPK1KDM4EL3MBTL1P4HTMP4HA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 307 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180148752-A1 | PROCESS FOR THE PREPARATION OF 2,4- OR 2,5-PYRIDINEDICARBOXYLIC ACID AND COPOLYMERS DERIVED THEREFROM | BIOME BIOPLASTICS LIMITED (GB) | 2018-05-31 | — | — | US | claimed |
| EP-3307901-A1 | PROCESS FOR THE PREPARATION OF 2,4- OR 2,5-PYRIDINEDICARBOXYLIC ACID AND COPOLYMERS DERIVED THEREFROM | Biome Bioplastics Limited (GB) | 2018-04-18 | — | — | EP | claimed |
| CN-104363887-B | Compositions, methods and uses comprising pyridine dicarboxylic acid esters and esters of glucose and fatty acids | 莱雅公司 | 2017-11-10 | — | — | CN | claimed |
| CN-107106452-A | Specific pyridinedicarboxylicacid acid derivatives/antioxidant combination | 欧莱雅 | 2017-08-29 | — | — | CN | claimed |
| WO-2016202875-A1 | PROCESS FOR THE PREPARATION OF 2,4- OR 2,5-PYRIDINEDICARBOXYLIC ACID AND COPOLYMERS DERIVED THEREFROM | BIOME BIOPLASTICS LIMITED (GB) | 2016-12-22 | — | — | WO | claimed |
| US-20050171346-A1 | Hexahydropyridazine-3-carboxylic acid derivatives, pharmaceutical compositions containing same and methods of preparation | AVENTIS PHARMA S.A. (FR) | 2005-08-04 | — | — | US | claimed |
| US-20260085336-A1 | NEW POLYMERS AND METHODS | BIOME BIOPLASTICS LTD (GB) | 2026-03-26 | — | — | US | disclosed |
| EP-3710428-B1 | MODULATORS OF THE INTEGRATED STRESS PATHWAY | CALICO LIFE SCIENCES LLC (US) | 2026-03-25 | — | — | EP | disclosed |
| EP-4658667-A1 | CYCLIC PEPTIDES FOR INHIBITING TNF RECEPTOR 1 ACTIVITY | Merck Sharp & Dohme LLC (US) | 2025-12-10 | — | — | EP | disclosed |
| US-12459929-B2 | GPCR receptor agonists, pharmaceutical compositions comprising the same, and methods for their use | CARMOT THERAPEUTICS INC. (US) | 2025-11-04 | — | — | US | disclosed |
| US-12454710-B2 | Process for the preparation of 2,4- or 2,5-pyridinedicarboxylic acid and copolymers derived therefrom | BIOME BIOPLASTICS LIMITED (GB) | 2025-10-28 | — | — | US | disclosed |
| US-20250269043-A1 | TARGETED BIFUNCTIONAL DEGRADERS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2025-08-28 | — | — | US | disclosed |
| US-20250270475-A1 | FABRIC AND HOME CARE COMPOSITION COMPRISING SURFACTANT AND A POLYESTER | THE PROCTER & GAMBLE COMPANY | 2025-08-28 | — | — | US | disclosed |
| CN-1076691-A | Sulfonamido-and sulfonamidocarbonyl-pyridine-2-carboxamides and their pyridine-N-oxides | HOECHST AG (DE) | 1993-09-29 | — | — | CN | disclosed |
| EP-0267794-B1 | PROCESS FOR PREPARING POLYOLEFINS | Nippon Petrochemicals Co., Ltd. (JP) | 1993-05-05 | — | — | EP | disclosed |
| US-4904675-A | Phamacologically active 5-carboxy-2-(5-tetrazolyl) pyridines | ZYMA SA (CH) | 1990-02-27 | — | — | US | disclosed |
| EP-0278908-A2 | Heterocyclic compounds | Zyma SA (CH) | 1988-08-17 | — | — | EP | disclosed |
| EP-0267794-A2 | Process for preparing polyolefins | Nippon Petrochemicals Co., Ltd. (JP) | 1988-05-18 | — | — | EP | disclosed |
| US-4525555-A | TITANIUM COMPOUND SUPPORTED ON SOLID REACTION PRODUCT OF MAGNESIUM HALIDE, SILOXANES, ORGANIC COMPOUNDS | NIPPON OIL COMPANY, LIMITED (JP) | 1985-06-25 | — | — | US | disclosed |
| US-4273779-A | Treating hypertension with substituted-5-amino-2-pyridinecarboxylic acids | CIBA-GEIGY CORPORATION (US) | 1981-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250269043-A1 | TARGETED BIFUNCTIONAL DEGRADERS | SMURF2, SMURF1, MDM2 | MAPK1 4334/4885KDM4E 1052/4885L3MBTL1 1396/4885 |
| US-12459929-B2 | GPCR receptor agonists, pharmaceutical compositions comprising the same, and methods for their use | GLP1R, GCGR, GIPR | MAPK1 1342/4885KDM4E 3526/4885L3MBTL1 4709/4885 |
| US-12454710-B2 | Process for the preparation of 2,4- or 2,5-pyridinedicarboxylic acid and copolymers derived therefrom | HPD, PCCA, MVD | MAPK1 2904/4885KDM4E 657/4885L3MBTL1 4344/4885 |
| US-20260085336-A1 | NEW POLYMERS AND METHODS | PGD, HPD, UROD | MAPK1 4122/4885KDM4E 286/4885L3MBTL1 4524/4885 |
| US-20050171346-A1 | Hexahydropyridazine-3-carboxylic acid derivatives, pharmaceutical compositions containing same and methods of preparation | HEXD, CDK5, CHUK | MAPK1 88/4885KDM4E 2612/4885L3MBTL1 4847/4885 |
| US-20180148752-A1 | PROCESS FOR THE PREPARATION OF 2,4- OR 2,5-PYRIDINEDICARBOXYLIC ACID AND COPOLYMERS DERIVED THEREFROM | HPD, PCCA, MVD | MAPK1 2904/4885KDM4E 657/4885L3MBTL1 4344/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.