SCHEMBL7941409

SCHEMBL7941409

CC1(c2cc(C(=O)OCCO)ccc2O)CCCCC1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RARB P10826 4/20 0.50
RARG P13631 4/20 0.50
RARA P10276 3/20 0.50
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
KDM4E B2RXH2 2/20 0.43
POLB P06746 1/20 0.43
HDAC6 Q9UBN7 1/20 0.43
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
CA7 P43166 1/20 0.42
CA9 Q16790 1/20 0.42
CA14 Q9ULX7 1/20 0.42
ESR1 P03372 3/20 0.42
HSD17B2 P37059 1/20 0.39
PTGDR Q13258 1/20 0.38
PTGDR2 Q9Y5Y4 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
PTPN11 Q06124 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7940436 0.86 RARA (0.55) RARBRARGRARAMEN1KMT2A
SCHEMBL7940323 0.82 ESR1 (0.47) RARBRARGRARAMEN1KMT2A
SCHEMBL7940424 0.81 GLA (0.41) RARBRARGRARAMEN1KMT2A
SCHEMBL8400868 0.80 YWHAG (0.47) RARBRARGRARAKDM4EPTGDR
SCHEMBL8595689 0.79 GLA (0.38) RARBRARGRARAMEN1KMT2A
SCHEMBL7943184 0.78 APP (0.51) RARBRARGRARAPTGDRPTGDR2
SCHEMBL7942020 0.78 SLC29A1 (0.38) RARBRARGRARAMEN1KMT2A
SCHEMBL3809004 0.77 RARB (0.74) RARBRARGRARAKDM4EPOLB
SCHEMBL7933836 0.77 SLC29A1 (0.38) RARBRARGRARAMEN1KMT2A
SCHEMBL23047456 0.75 CA12 (0.66) KDM4EPOLBHDAC6CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6242514-B1 CYCLIC PHOSPHATE OR PHOSPHONATE; HEAT AND OXIDATION STABILIZER ESPECIALLY FOR OLEFIN POLYMERS AND ENGINEERING THERMOPLASTICS SUMITOMO CHEMICAL COMPANY, LTD. (JP) 2001-06-05 US disclosed
US-5914361-A IMPART HEAT STABILITY TO ORGANIC MATERIALS, INCLUDING POLYOLEFINS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-06-22 US disclosed
EP-0861847-A2 Stabilizer composition and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-09-02 EP disclosed