SCHEMBL7933836

SCHEMBL7933836

CCc1cc(C(=O)OCCO)cc(C2(C)CCCCC2)c1OC

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC29A1 Q99808 7/20 0.38
SCN1A P35498 2/20 0.37
SCN2A Q99250 2/20 0.37
SCN3A Q9NY46 2/20 0.37
SMN1; SMN2 Q16637 3/20 0.37
MEN1 O00255 3/20 0.37
KMT2A Q03164 3/20 0.37
LMNA P02545 2/20 0.37
CYP3A4 P08684 2/20 0.37
CYP2D6 P10635 2/20 0.37
THPO P40225 2/20 0.37
MTOR P42345 2/20 0.37
ABCC4 O15439 1/20 0.37
CYP2C9 P11712 1/20 0.37
TSHR P16473 1/20 0.37
CHRM3 P20309 1/20 0.37
HTR2A P28223 1/20 0.37
MAPK1 P28482 1/20 0.37
SLC6A4 P31645 1/20 0.37
CYP2C19 P33261 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7942020 0.87 SLC29A1 (0.38) SLC29A1SCN1ASCN2ASCN3ASMN1; SMN2
SCHEMBL7940424 0.86 GLA (0.41) MEN1KMT2ATSHRRARARARB
SCHEMBL7786557 0.83 RARB (0.47) CYP3A4RARARARBRARGPTGDR
SCHEMBL8400745 0.82 KMT2A (0.40) SMN1; SMN2MEN1KMT2ALMNARARA
SCHEMBL7941069 0.80 ALDH1A1 (0.37) KMT2ARARARARBRARG
SCHEMBL7940436 0.79 RARA (0.55) SMN1; SMN2MEN1KMT2ALMNATSHR
SCHEMBL7940323 0.77 ESR1 (0.47) MEN1KMT2ATSHRRARARARB
SCHEMBL6568848 0.77 RARB (0.36) MEN1KMT2ACYP3A4TSHRRARA
SCHEMBL7941409 0.77 RARB (0.50) SMN1; SMN2MEN1KMT2ATSHRRARA
SCHEMBL7944751 0.75 THRB (0.39) SLC29A1SCN1ASCN2ASCN3ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6242514-B1 CYCLIC PHOSPHATE OR PHOSPHONATE; HEAT AND OXIDATION STABILIZER ESPECIALLY FOR OLEFIN POLYMERS AND ENGINEERING THERMOPLASTICS SUMITOMO CHEMICAL COMPANY, LTD. (JP) 2001-06-05 US disclosed
US-5914361-A IMPART HEAT STABILITY TO ORGANIC MATERIALS, INCLUDING POLYOLEFINS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-06-22 US disclosed
US-5891939-A POLYMER STABILIZERS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-04-06 US disclosed