Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NPY1R | P25929 | 1/20 | 0.36 |
| ▸ | NPY2R | P49146 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 6/20 | 0.33 |
| ▸ | PPARA | Q07869 | 6/20 | 0.33 |
| ▸ | PPARD | Q03181 | 3/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7941499 | 1.00 | ALOX15 (0.36) | ALOX15MAPTNPY1RNPY2RALDH1A1 | |
| SCHEMBL7941464 | 0.83 | PPARG (0.38) | MAPTNPY1RNPY2RALDH1A1PDE4B | |
| SCHEMBL7941466 | 0.83 | PPARG (0.38) | MAPTNPY1RNPY2RALDH1A1PDE4B | |
| SCHEMBL16202056 | 0.80 | MAPT (0.50) | MAPTNPY1RNPY2RALDH1A1PPARG | |
| SCHEMBL7942916 | 0.80 | GAA (0.45) | ALOX15MAPTALDH1A1PDE4BPPARG | |
| SCHEMBL7942918 | 0.80 | GAA (0.45) | ALOX15MAPTALDH1A1PDE4BPPARG | |
| SCHEMBL2051172 | 0.77 | NPC1 (0.44) | ALOX15MAPTNPY1RNPY2RALDH1A1 | |
| SCHEMBL9222646 | 0.77 | NPC1 (0.44) | ALOX15MAPTNPY1RNPY2RALDH1A1 | |
| SCHEMBL2051174 | 0.77 | NPC1 (0.44) | ALOX15MAPTNPY1RNPY2RALDH1A1 | |
| SCHEMBL16683793 | 0.74 | TSHR (0.39) | ALOX15MAPTNPY1RNPY2RALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6274586-B1 | SYNERGISTIC MIXTURE WITH METHYL (N-METHOXY)-PHENYLCARBAMATE DERIVATIVE | BASF AKTIENGESELLSCHAFT (DE) | 2001-08-14 | — | — | US | claimed |