SCHEMBL7941466

SCHEMBL7941466

[CH]Oc1ccc(C(C)=NOCC)cc1C

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARG P37231 7/20 0.38
PPARA Q07869 7/20 0.38
PPARD Q03181 3/20 0.38
LMNA P02545 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
PTBP1 P26599 1/20 0.38
MAPK1 P28482 1/20 0.37
HTT P42858 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
ALDH1A1 P00352 1/20 0.36
TAS1R3 Q7RTX0 1/20 0.36
TAS1R1 Q7RTX1 1/20 0.36
PKM P14618 1/20 0.34
HPGD P15428 1/20 0.34
GABRA1 P14867 1/20 0.34
GABRG2 P18507 1/20 0.34
GABRB3 P28472 1/20 0.34
GABRA5 P31644 1/20 0.34
GABRA3 P34903 1/20 0.34
GABRA2 P47869 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7941464 1.00 PPARG (0.38) PPARGPPARAPPARDLMNASMN1; SMN2
SCHEMBL7942914 0.84 GAA (0.41) PPARGPPARAPPARDL3MBTL1ALDH1A1
SCHEMBL7942915 0.84 GAA (0.41) PPARGPPARAPPARDL3MBTL1ALDH1A1
SCHEMBL7941499 0.83 ALOX15 (0.36) PPARGPPARAPPARDALDH1A1TAS1R3
SCHEMBL7941496 0.83 ALOX15 (0.36) PPARGPPARAPPARDALDH1A1TAS1R3
SCHEMBL16202057 0.82 PPARG (0.51) PPARGPPARALMNASMN1; SMN2PTBP1
SCHEMBL17217588 0.80 NPC1 (0.48) PPARGPPARALMNASMN1; SMN2PTBP1
SCHEMBL15851161 0.80 NPC1 (0.48) PPARGPPARALMNASMN1; SMN2PTBP1
SCHEMBL16202082 0.76 LMNA (0.41) PPARGPPARALMNASMN1; SMN2PTBP1
SCHEMBL13683674 0.73 SMN1; SMN2 (0.52) PPARGPPARALMNASMN1; SMN2PTBP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6274586-B1 SYNERGISTIC MIXTURE WITH METHYL (N-METHOXY)-PHENYLCARBAMATE DERIVATIVE BASF AKTIENGESELLSCHAFT (DE) 2001-08-14 US claimed