Methacrylic Acid

Methacrylic Acid

SCHEMBL5145666

C=C(C)C(=O)O.CC(CO)CCC(C)CO

nearest known ligand 0.44

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.44
TGFBR1 P36897 1/20 0.41
ACE2 Q9BYF1 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
BHMT Q93088 1/20 0.31
BHMT2 Q9H2M3 1/20 0.31
BLM P54132 1/20 0.30
GABRP O00591 2/20 0.30
GABRD O14764 2/20 0.30
GABRA1 P14867 2/20 0.30
GABRB1 P18505 2/20 0.30
GABRG2 P18507 2/20 0.30
GABRB3 P28472 2/20 0.30
GABRA5 P31644 2/20 0.30
GABRA3 P34903 2/20 0.30
GABRA2 P47869 2/20 0.30
GABRB2 P47870 2/20 0.30
GABRA4 P48169 2/20 0.30
GABRE P78334 2/20 0.30
GABRA6 Q16445 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL4526194 1.00 TSHR (0.44) TSHRTGFBR1ACE2TDP1BHMT
Methacrylic Acid SCHEMBL3319371 0.90 TGFBR1 (0.43) TSHRTGFBR1TDP1
Methacrylic Acid SCHEMBL9779579 0.90 TGFBR1 (0.43) TSHRTGFBR1TDP1
Methacrylic Acid SCHEMBL9779539 0.90 TGFBR1 (0.43) TSHRTGFBR1TDP1
Methacrylic Acid SCHEMBL9779254 0.90 TGFBR1 (0.43) TSHRTGFBR1TDP1
Methacrylic Acid SCHEMBL7941584 0.89 TSHR (0.62) TSHRTGFBR1ACE2TDP1
Methacrylic Acid SCHEMBL10400354 0.84 LMNA (0.36) TSHRTGFBR1ACE2BLM
Methacrylic Acid SCHEMBL1930348 0.84 ACE2 (0.38) TSHRTGFBR1ACE2BLM
Methacrylic Acid SCHEMBL5683702 0.82 TSHR (0.50) TSHRTGFBR1TDP1
Methacrylic Acid SCHEMBL9397155 0.82 TSHR (0.50) TSHRTGFBR1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8349779-B2 Polymers with h-bridge forming functionalities EVONIK ROHMAX ADDITIVES GMBH (DE) 2013-01-08 US claimed
EP-3515402-B1 (METH)ACRYLATE BASED RESIN BINDER COMPOSITION ROEHM AMERICA LLC (US) 2024-11-27 EP disclosed
CN-114174238-B Low odor and low emission particulate materials and related coatings 赛德克公众有限公司 2023-05-05 CN disclosed
CN-109789078-B (meth) acrylate-based resin binder composition 赢创有限公司 2022-10-04 CN disclosed
US-11279832-B2 (Meth)acrylate based resin binder composition ROEHM GMBH (DE) 2022-03-22 US disclosed
CN-114174238-A Particulate materials and related coatings, especially architectural element coatings, with low odor and low emissions, e.g. floor coatings based on free radical polymerization 赛德克公众有限公司 2022-03-11 CN disclosed
US-20190264042-A1 (METH)ACRYLATE BASED RESIN BINDER COMPOSITION EVONIK ROEHM GMBH (DE) 2019-08-29 US disclosed
US-8722600-B2 Polymers with H-bridge forming functionalities for improving anti-wear protection EVONIK ROHMAX ADDITIVES GMBH (DE) 2014-05-13 US disclosed
US-8349779-B2 Polymers with h-bridge forming functionalities EVONIK ROHMAX ADDITIVES GMBH (DE) 2013-01-08 US disclosed
US-20070197409-A1 Polymers with h-bridge forming functionalities for improving anti-wear protection EVONIK DEGUSSA GMBH (DE) 2007-08-23 US disclosed
US-20070184993-A1 Polymers with h-bridge forming functionalities ROHMAX ADDITIVES GMBH (DE) 2007-08-09 US disclosed
US-7049355-B2 Low-odor, cold-curing (METH) acrylate reaction resin for floor coating, a floor coating containing the reaction resin, and a process for the preparation of the floor coating ROEHM GMBH & CO. KG (DE) 2006-05-23 US disclosed
US-6639029-B1 Atom trasfer radical polymerization of acrylate esters using copper metal catalyst; narrow molecular weight distribution; high molecular weight ROHMAX ADDITIVES GMBH (DE) 2003-10-28 US disclosed
US-6610802-B2 Polymerizing unsatd. monomers with a transition metal catalyst and a coordination compound-forming ligand; filtration using a filter aid having carboxylic acid-, sulfonic acid- or phosphonic acid-containing units ROHMAX ADDITIVES GMBH (DE) 2003-08-26 US disclosed
US-6610801-B1 Acrylates with alkyl chains with at least 8 carbons; narrow molecular weight distribution; high molecular weight; ligands form a coordination compound with copper catalyst; initiator containing a transferable group (halide, sulfonyl halide) ROHMAX ADDITIVES GMBH (DE) 2003-08-26 US disclosed
US-20030060587-A1 Process for synthesis of polymer compositions, polymer compositions obtainable by the process, and use of the same ROHMAX ADDITIVES GMBH (DE) 2003-03-27 US disclosed
US-20020002259-A1 LOW-ODOR, COLD-CURING (METH) ACRYLATE REACTION RESIN FOR FLOOR COATING, A FLOOR COATING CONTAINING THE REACTION RESIN, AND A PROCESS FOR THE PREPARATION OF THE FLOOR COATING ROEHM GMBH & CO KG (DE) 2002-01-03 US disclosed