Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3773038 | 1.00 | LTA4H (0.38) | LTA4HCHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL45553 | 0.98 | LTA4H (0.39) | LTA4HCHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL7227482 | 0.79 | HRH3 (0.43) | LTA4HCHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL10748748 | 0.79 | HRH3 (0.43) | LTA4HCHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL23872301 | 0.79 | HRH3 (0.43) | LTA4HCHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL23872300 | 0.76 | LTA4H (0.42) | LTA4HCHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL5466976 | 0.72 | CHRNB2 (0.41) | LTA4HCHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL5233749 | 0.72 | CHRNB2 (0.41) | LTA4HCHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL28207021 | 0.71 | SMN1; SMN2 (0.39) | LTA4HCHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL18306306 | 0.71 | SMN1; SMN2 (0.39) | LTA4HCHRNB2CHRNB4CHRNA3CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242438-B1 | 3-Azetidinylalkylpiperidines or -pyrrolidines as tachykinin antagonists | PFIZER INC. | 2001-06-05 | — | — | US | disclosed |