Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT6 | P42226 | 1/20 | 0.45 |
| ▸ | CYP51A1 | Q16850 | 4/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | CCKBR | P32239 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | CCR1 | P32246 | 1/20 | 0.39 |
| ▸ | PYGL | P06737 | 2/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | PLG | P00747 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7945428 | 0.94 | STAT6 (0.44) | STAT6CYP51A1DRD2CCKBRCCR1 | |
| SCHEMBL7942838 | 0.94 | STAT6 (0.44) | STAT6CYP51A1DRD2CCKBRCCR1 | |
| SCHEMBL7941166 | 0.91 | STAT6 (0.43) | STAT6CYP51A1DRD2CCKBRCCR1 | |
| SCHEMBL7933535 | 0.91 | STAT6 (0.43) | STAT6CYP51A1DRD2CCKBRCCR1 | |
| SCHEMBL7945425 | 0.91 | STAT6 (0.42) | STAT6CYP51A1DRD2CCKBRPYGL | |
| SCHEMBL14980442 | 0.91 | STAT6 (0.48) | STAT6CYP51A1DRD2CCKBRHRH4 | |
| SCHEMBL7934440 | 0.91 | STAT6 (0.48) | STAT6CYP51A1DRD2CCKBRHRH4 | |
| SCHEMBL7941165 | 0.90 | STAT6 (0.46) | STAT6CYP51A1DRD2AKR1C3 | |
| SCHEMBL7941012 | 0.90 | STAT6 (0.47) | STAT6CYP51A1DRD2CCKBRPYGL | |
| SCHEMBL7941160 | 0.89 | STAT6 (0.45) | STAT6CYP51A1DRD2CCKBRHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010011912-A1 | TRPV4 ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2010-01-28 | — | — | WO | disclosed |