Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT6 | P42226 | 1/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 7/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | F10 | P00742 | 1/20 | 0.45 |
| ▸ | PLG | P00747 | 1/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.45 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | CYP51A1 | Q16850 | 1/20 | 0.44 |
| ▸ | CCKBR | P32239 | 1/20 | 0.43 |
| ▸ | RBP4 | P02753 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7934440 | 1.00 | STAT6 (0.48) | STAT6AKR1C3F2F10PLG | |
| SCHEMBL7934126 | 0.94 | STAT6 (0.48) | STAT6AKR1C3F2F10PLG | |
| SCHEMBL7941160 | 0.92 | STAT6 (0.45) | STAT6HRH4DRD2CYP51A1CCKBR | |
| SCHEMBL7945427 | 0.92 | STAT6 (0.45) | STAT6AKR1C3F2F10PLG | |
| SCHEMBL7941646 | 0.91 | STAT6 (0.45) | STAT6AKR1C3F2F10PLG | |
| SCHEMBL7943270 | 0.90 | STAT6 (0.48) | STAT6AKR1C3HRH4DRD2CYP51A1 | |
| SCHEMBL7942667 | 0.89 | STAT6 (0.44) | STAT6AKR1C3F2F10PLG | |
| SCHEMBL7942685 | 0.89 | STAT6 (0.47) | STAT6AKR1C3F2F10PLG | |
| SCHEMBL7943634 | 0.89 | STAT6 (0.48) | STAT6AKR1C3DRD2CYP51A1CCKBR | |
| SCHEMBL7942838 | 0.89 | STAT6 (0.44) | STAT6F2F10PLGPRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8450484-B2 | TRPV4 antagonists | GlaxoSmithKline, LLC (US) | 2013-05-28 | — | — | US | disclosed |