Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT6 | P42226 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 3/20 | 0.41 |
| ▸ | CYP51A1 | Q16850 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.39 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.39 |
| ▸ | FLT3 | P36888 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7945428 | 0.92 | STAT6 (0.44) | STAT6DRD3CYP51A1ALOX15DRD2 | |
| SCHEMBL7941646 | 0.90 | STAT6 (0.45) | STAT6CYP51A1AKR1C3DRD2 | |
| SCHEMBL7941166 | 0.89 | STAT6 (0.43) | STAT6CYP51A1ELANEALOX15DRD2 | |
| SCHEMBL7943634 | 0.89 | STAT6 (0.48) | STAT6DRD3CYP51A1NPC1RAB9A | |
| SCHEMBL7941012 | 0.88 | STAT6 (0.47) | STAT6DRD3CYP51A1FLT3AKR1C3 | |
| SCHEMBL7942838 | 0.87 | STAT6 (0.44) | STAT6DRD3CYP51A1ALOX15DRD2 | |
| SCHEMBL19856974 | 0.87 | NPC1 (0.42) | STAT6DRD3CYP51A1NPC1RAB9A | |
| SCHEMBL7942670 | 0.86 | STAT6 (0.43) | STAT6DRD3CYP51A1AKR1C3DRD2 | |
| SCHEMBL14980442 | 0.86 | STAT6 (0.48) | STAT6CYP51A1AKR1C3DRD2 | |
| SCHEMBL7934440 | 0.86 | STAT6 (0.48) | STAT6CYP51A1AKR1C3DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010011912-A1 | TRPV4 ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2010-01-28 | — | — | WO | disclosed |