Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 6/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL441644 | 0.78 | MEN1 (0.47) | MEN1KMT2AUSP2ATMKEAP1 | |
| SCHEMBL23934280 | 0.78 | MEN1 (0.41) | MEN1KMT2AUSP2ATMKEAP1 | |
| SCHEMBL17316947 | 0.76 | MEN1 (0.40) | MEN1KMT2AUSP2ATMKEAP1 | |
| SCHEMBL11553071 | 0.74 | MEN1 (0.50) | MEN1KMT2AUSP2ATMKEAP1 | |
| SCHEMBL9400286 | 0.72 | ALDH1A1 (0.36) | MEN1KMT2AUSP2ATMKEAP1 | |
| SCHEMBL9400279 | 0.69 | APP (0.42) | MEN1KMT2AUSP2ATMKEAP1 | |
| SCHEMBL2036747 | 0.69 | MEN1 (0.58) | MEN1KMT2AUSP2ATMKEAP1 | |
| SCHEMBL4870220 | 0.69 | APP (0.42) | MEN1KMT2AUSP2ATMKEAP1 | |
| SCHEMBL17429229 | 0.69 | MEN1 (0.41) | MEN1KMT2AUSP2ATMKEAP1 | |
| SCHEMBL23934207 | 0.69 | THRB (0.50) | MEN1KMT2AUSP2ATMKEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6191307-B1 | Process for making benzoic acids | ALBEMARLE CORPORATION | 2001-02-20 | — | — | US | disclosed |