Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.57 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.40 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9768615 | 0.81 | TAAR1 (0.53) | TAAR1AOC3SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6014574 | 0.80 | TAAR1 (0.54) | TAAR1AOC3HTR2ALMNAKDM4E | |
| SCHEMBL19762907 | 0.76 | TAAR1 (0.55) | TAAR1AOC3SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL5351663 | 0.73 | TAAR1 (1.00) | TAAR1AOC3SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL5005843 | 0.73 | TAAR1 (1.00) | TAAR1AOC3SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL247628 | 0.73 | TAAR1 (1.00) | TAAR1AOC3SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL29790456 | 0.72 | AOC3 (0.48) | TAAR1AOC3SLC6A2SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL1669712 | 0.71 | TAAR1 (0.95) | TAAR1AOC3SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6014398 | 0.71 | TAAR1 (0.52) | TAAR1AOC3 | |
| SCHEMBL598978 | 0.70 | TAAR1 (0.64) | TAAR1AOC3SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242002-B1 | RAPIDLY DISINTEGRATING ORAL DOSAGE FORM OF ALKALI-SENSITIVE MATERIAL, EFFERVESCENT BASE OF ALKALINE EARTH METAL CARBONATE, ORGANIC EDIBLE ACID AND ALKALI METAL SALT OF CITRIC ACID, AUXILIARY INGREDIENTS | ARZNEIMITTELWERK DRESDEN GMBH (DE) | 2001-06-05 | — | — | US | disclosed |