Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 1.00 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.60 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.60 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.60 |
| ▸ | HTR2A | P28223 | 2/20 | 0.54 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.47 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.45 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.45 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5351663 | 1.00 | TAAR1 (1.00) | TAAR1SLC6A4SLC6A3SLC6A2HTR2A | |
| SCHEMBL5005843 | 1.00 | TAAR1 (1.00) | TAAR1SLC6A4SLC6A3SLC6A2HTR2A | |
| Hydrochloric Acid SCHEMBL1669712 | 0.98 | TAAR1 (0.95) | TAAR1SLC6A4SLC6A3SLC6A2HTR2A | |
| Acetamide SCHEMBL8830920 | 0.88 | TAAR1 (0.78) | TAAR1SLC6A4SLC6A3SLC6A2HTR2A | |
| SCHEMBL8995001 | 0.85 | TAAR1 (0.73) | TAAR1SLC6A4SLC6A3SLC6A2HTR2A | |
| SCHEMBL4695342 | 0.84 | TAAR1 (0.72) | TAAR1SLC6A4SLC6A3SLC6A2HTR2A | |
| SCHEMBL9055834 | 0.82 | TAAR1 (0.69) | TAAR1SLC6A4SLC6A3SLC6A2HTR2A | |
| SCHEMBL8953218 | 0.82 | TAAR1 (0.69) | TAAR1SLC6A4SLC6A3SLC6A2HTR2A | |
| SCHEMBL11679334 | 0.80 | TAAR1 (0.67) | TAAR1SLC6A4SLC6A3SLC6A2HTR2A | |
| SCHEMBL18634216 | 0.80 | TAAR1 (0.64) | TAAR1SLC6A4SLC6A3SLC6A2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 143 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190292164-A1 | PROCESS FOR THE PREPARATION OF GLYCEROL CARBONATE | THE QUEEN'S UNIVERSITY OF BELFAST (GB) | 2019-09-26 | — | — | US | claimed |
| CN-101838195-A | Chemical resolution preparation method for optical pure Beta-3, 4-dyhydroxyophenyl lactic acid | TIANJIN TASLY PHARMACEUTICAL | 2010-09-22 | — | — | CN | claimed |
| US-7790900-B2 | Method for producing an optically active nitro compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-09-07 | — | — | US | claimed |
| US-20080281125-A1 | Process for Preparing Enantiopure E-(2S)-Alkyl-5-Halopent-4-Enoic Acids and Esters | DSM FINE CHEMICALS AUSTRIA NFG GMBH & CO KG (AT) | 2008-11-13 | — | — | US | claimed |
| CN-101137602-A | Process for preparing enantiomerically pure E- (2S) -alkyl-5-halopent-4-enoic acids and esters thereof | DSM FINE CHEM AUSTRIA GMBH (AT) | 2008-03-05 | — | — | CN | claimed |
| EP-1856008-A1 | PROCESS FOR PREPARING ENANTIOPURE E-(2S)-ALKYL-5-HALOPENT-4-ENOIC ACIDS AND ESTERS | DSM Fine Chemicals Austria Nfg GmbH & Co KG (AT) | 2007-11-21 | — | — | EP | claimed |
| US-7214820-B2 | Process for producing optically active flurbiprofen | NAGASE & CO., LTD. (JP) | 2007-05-08 | — | — | US | claimed |
| WO-2006099926-A1 | PROCESS FOR PREPARING ENANTIOPURE E-(2S)-ALKYL-5-HALOPENT-4-ENOIC ACIDS AND ESTERS | DSM FINE CHEMICALS AUSTRIA NFG GMBH & CO KG (AT) | 2006-09-28 | — | — | WO | claimed |
| US-20060135617-A1 | Process for producing optically active flurbiprofen | NAGASE & CO., LTD. (JP) | 2006-06-22 | — | — | US | claimed |
| EP-0906900-B1 | A process for preparing optically active 2-hydroxy-methyl-3-phenylpropionic acid | AJINOMOTO KK (JP) | 2002-01-23 | — | — | EP | claimed |
| US-6093846-A | BY REACTING WITH SPECIFIED OPTICALLY ACTIVE AMINES SUCH AS CIS-1-AMINO-2-INDANOL IN A SOLVENT, PRODUCING TWO DIASTEREOISOMERIC SALTS OF DIFFERING SOLUBILITY, FRACTIONAL CRYSTALLIZATION AND DECOMPOSING THE SALT WITH ALKALI OR ACID | AJINOMOTO CO., INC. (JP) | 2000-07-25 | — | — | US | claimed |
| US-5852209-A | Process for optically resolving 2-(3-benzoylphenyl) propionic acid | NAGASE & CO., LTD. (JP) | 1998-12-22 | — | — | US | claimed |
| EP-0529835-B1 | Optical resolution of (+/-)-2-(4-isobutylphenyl) propionic acid | NAGASE & CO LTD (JP) | 1997-01-22 | — | — | EP | claimed |
| EP-0703212-A1 | Process for optically resolving 2-(3-benzoylphenyl) propionic acid | NAGASE & COMPANY, LTD. (JP) | 1996-03-27 | — | — | EP | claimed |
| JP-8151344-A | — | — | None | — | — | JP | disclosed |
| JP-9056396-A | — | — | None | — | — | JP | disclosed |
| JP-11106363-A | — | — | None | — | — | JP | disclosed |
| EP-0146067-A2 | Novel substrates for D-amino acid oxidase | MERRELL DOW PHARMACEUTICALS INC. (US) | 1985-06-26 | — | — | EP | disclosed |
| US-4313978-A | Antistatic compositions and treatment | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1982-02-02 | — | — | US | disclosed |
| JP-H00956396-A | — | — | 0001-01-01 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060135617-A1 | Process for producing optically active flurbiprofen | QDPR, BLVRB, CYP3A5 | TAAR1 281/4885SLC6A4 131/4885SLC6A3 430/4885 |
| US-20190292164-A1 | PROCESS FOR THE PREPARATION OF GLYCEROL CARBONATE | GK, DGKI, DGKA | TAAR1 1356/4885SLC6A4 1830/4885SLC6A3 978/4885 |
| US-20080281125-A1 | Process for Preparing Enantiopure E-(2S)-Alkyl-5-Halopent-4-Enoic Acids and Esters | ENY2, RER1, EEF1E1 | TAAR1 392/4885SLC6A4 436/4885SLC6A3 495/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.