Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | HRH1 | P35367 | 2/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 3/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6014398 | 0.83 | TAAR1 (0.52) | TAAR1AOC3HRH1RIPK1 | |
| SCHEMBL7941653 | 0.81 | TAAR1 (0.57) | TAAR1PKMAOC3SLC6A2SLC6A4 | |
| SCHEMBL9918244 | 0.78 | TAAR1 (0.52) | TAAR1PKMAOC3SLC6A2SLC6A4 | |
| SCHEMBL9055834 | 0.75 | TAAR1 (0.69) | TAAR1PKMAOC3SLC6A2SLC6A4 | |
| SCHEMBL7511093 | 0.72 | TAAR1 (0.59) | TAAR1PKMAOC3SLC6A2SLC6A4 | |
| SCHEMBL7511084 | 0.72 | TAAR1 (0.59) | TAAR1PKMAOC3SLC6A2SLC6A4 | |
| SCHEMBL17755098 | 0.72 | TAAR1 (0.59) | TAAR1PKMAOC3SLC6A2SLC6A4 | |
| SCHEMBL5661323 | 0.71 | TAAR1 (0.57) | TAAR1PKMAOC3SLC6A2SLC6A4 | |
| SCHEMBL17363629 | 0.71 | TAAR1 (0.57) | TAAR1PKMSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL12073186 | 0.71 | TAAR1 (0.57) | TAAR1PKMSLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3005421-A | — | — | None | — | — | JP | disclosed |
| JP-H035421-A | ADMINISTRATION OF DEPRENYL MEDICINE SO AS TO REDUCE DANGER OF SIDE EFFECT | DONALD A BAISUKE | 1991-01-11 | — | — | JP | disclosed |