Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 2/20 | 0.70 |
| ▸ | RAB9A | P51151 | 4/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.67 |
| ▸ | HPGD | P15428 | 2/20 | 0.67 |
| ▸ | GALR3 | O60755 | 1/20 | 0.67 |
| ▸ | MEN1 | O00255 | 6/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.66 |
| ▸ | LMNA | P02545 | 3/20 | 0.66 |
| ▸ | NPC1 | O15118 | 2/20 | 0.65 |
| ▸ | MAPT | P10636 | 3/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31503975 | 0.90 | LMNA (0.78) | MLYCDRAB9AALDH1A1TDP1MEN1 | |
| SCHEMBL3498895 | 0.87 | LMNA (0.78) | MLYCDRAB9AALDH1A1HPGDMEN1 | |
| SCHEMBL30776636 | 0.86 | MLYCD (0.68) | MLYCDRAB9AALDH1A1TDP1MEN1 | |
| SCHEMBL2833331 | 0.85 | MAPT (0.75) | MLYCDRAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL2833532 | 0.85 | MLYCD (0.67) | MLYCDRAB9AALDH1A1TDP1MEN1 | |
| SCHEMBL5645175 | 0.84 | LMNA (0.69) | MLYCDRAB9AALDH1A1TDP1MEN1 | |
| SCHEMBL2950269 | 0.83 | HIF1A (0.77) | RAB9AALDH1A1TDP1GALR3MEN1 | |
| SCHEMBL11439450 | 0.83 | NPC1 (0.71) | MLYCDRAB9AALDH1A1TDP1MEN1 | |
| SCHEMBL20620003 | 0.83 | MEN1 (0.71) | MLYCDRAB9AALDH1A1HPGDMEN1 | |
| SCHEMBL17549811 | 0.83 | MEN1 (0.70) | MLYCDRAB9AALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6245817-B1 | NEUROPEPTIDE Y | BAYER CORPORATION | 2001-06-12 | — | — | US | disclosed |
| US-5939462-A | ADMINISTERING ALKOXY AND -THIOALKOXYAMIDE COMPOSITIONS TO MAMMALS TO TREAT DISORDERS SUCH AS OBESITY THAT ARE MEDIATED BY NEUROPEPTIDE Y (?NPY?) | BAYER CORPORATION (US) | 1999-08-17 | — | — | US | disclosed |