Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 4/20 | 0.47 |
| ▸ | PLAU | P00749 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | PFKFB4 | Q16877 | 2/20 | 0.46 |
| ▸ | PFKFB3 | Q16875 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL794304 | 0.83 | PFKFB3 (0.63) | HTTLMNAALDH1A1PFKFB4PFKFB3 | |
| SCHEMBL27943370 | 0.83 | MMP2 (0.59) | TP53HTTLMNAALDH1A1PKM | |
| SCHEMBL793607 | 0.82 | PFKFB4 (0.64) | HTTLMNAALDH1A1PFKFB4PFKFB3 | |
| SCHEMBL793433 | 0.81 | PFKFB4 (0.67) | TP53PLAUHTTLMNAALDH1A1 | |
| SCHEMBL6792745 | 0.81 | CA12 (0.74) | CA12CA9PLAUHTTLMNA | |
| SCHEMBL793299 | 0.80 | PFKFB3 (0.65) | PLAUHTTLMNATSHRPKM | |
| SCHEMBL793359 | 0.80 | PFKFB3 (0.68) | TP53PLAUHTTLMNAALDH1A1 | |
| SCHEMBL793619 | 0.77 | PFKFB3 (0.71) | TP53LMNAPKMPFKFB4PFKFB3 | |
| SCHEMBL793788 | 0.77 | PFKFB3 (0.59) | TP53LMNAPKMPFKFB4PFKFB3 | |
| SCHEMBL795004 | 0.76 | PFKFB3 (0.60) | TP53LMNAPFKFB4PFKFB3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2616450-A2 | SULFONAMIDE COMPOUNDS | Kancera AB (SE) | 2013-07-24 | — | — | EP | disclosed |
| WO-2012035171-A2 | NEW COMPOUNDS | KANCERA AB (SE) | 2012-03-22 | — | — | WO | disclosed |