SCHEMBL794181

SCHEMBL794181

[CH2]C(c1ccccc1)C(C)c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MIF P14174 2/20 0.41
TAAR1 Q96RJ0 3/20 0.41
ADRA2A P08913 1/20 0.39
ADRA2C P18825 1/20 0.39
CYP2D6 P10635 1/20 0.39
LMNA P02545 1/20 0.39
HIF1A Q16665 1/20 0.39
KDM4E B2RXH2 1/20 0.39
ALDH1A1 P00352 1/20 0.38
DPP4 P27487 2/20 0.38
F2 P00734 1/20 0.38
TSHR P16473 1/20 0.38
CACNA1F O60840 1/20 0.38
CHRM2 P08172 1/20 0.38
CHRM1 P11229 1/20 0.38
ADRA2B P18089 1/20 0.38
CHRM3 P20309 1/20 0.38
ADRA1A P35348 1/20 0.38
HRH1 P35367 1/20 0.38
OPRK1 P41145 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10793335 0.89 LMNA (0.41) MIFLMNAKDM4ETSHROPRK1
SCHEMBL9211272 0.81 MIF (0.43) MIFTAAR1ADRA2AADRA2CCYP2D6
SCHEMBL1989835 0.81 TSHR (0.46) MIFTAAR1ADRA2AADRA2CCYP2D6
SCHEMBL908216 0.80 TAAR1 (0.50) MIFTAAR1ADRA2AADRA2CCYP2D6
SCHEMBL7940847 0.80 DPP4 (0.47) MIFTAAR1CYP2D6LMNADPP4
SCHEMBL27489318 0.79 TSHR (0.43) MIFTAAR1ADRA2AADRA2CCYP2D6
SCHEMBL9205897 0.79 DPP4 (0.50) MIFTAAR1ADRA2AADRA2CLMNA
SCHEMBL27418456 0.79 MIF (0.41) MIFTAAR1ADRA2AADRA2CCYP2D6
SCHEMBL28986399 0.77 ADRA2A (0.54) MIFTAAR1ADRA2AADRA2CCYP2D6
SCHEMBL28466803 0.77 LMNA (0.48) MIFADRA2AADRA2CCYP2D6LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001052868-A9 COMBINATIONS FOR TREATING NEOPLASMS YU BAOFA (US) 2003-01-16 WO claimed
CN-109803969-B 2-phenylphenoxy substituted perylene bisimide compounds and uses thereof 巴斯夫欧洲公司 2022-08-05 CN disclosed
CN-113166063-A Pesticidal compounds 巴斯夫欧洲公司 2021-07-23 CN disclosed
EP-2589643-B1 HIGHLY EFFICIENT CARBAZOLE-BASED COMPOUND, AND ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING SAME SK CHEMICALS CO LTD (KR) 2017-09-20 EP disclosed
EP-2139835-B1 METHOD FOR SYNTHESIZING OPTICALLY ACTIVE CARBONYL COMPOUNDS BASF SE (DE) 2017-05-10 EP disclosed
EP-2352719-B1 METHOD FOR PRODUCING N,N-SUBSTITUTED-3-AMINOPROPAN-1-OLS BASF SE (DE) 2016-06-08 EP disclosed
CN-102569893-B Nonaqueous electrolyte solution for secondary battery and nonaqueous electrolyte secondary battery using same MITSUBISHI CHEMICAL CORP. (JP) 2016-05-11 CN disclosed
US-9142784-B2 Highly efficient carbazole-based compound, and organic electroluminescence device comprising same SK CHEMICALS CO., LTD. (KR) 2015-09-22 US disclosed
EP-2616429-B1 METHOD FOR PRODUCING AROMATIC AMINES BASF SE (DE) 2015-08-05 EP disclosed
EP-2616429-A1 METHOD FOR PRODUCING AROMATIC AMINES BASF SE (DE) 2013-07-24 EP disclosed
WO-2001052868-A9 COMBINATIONS FOR TREATING NEOPLASMS YU BAOFA (US) 2003-01-16 WO disclosed
US-20020068801-A1 Photosensitive diacrylate and dimethacrylate compositions HUNTSMAN INTERNATIONAL LLC 2002-06-06 US disclosed
US-6316552-B1 USED IN PHOTOSENSITIVE FORMULATIONS WHICH ARE USED IN PREPARATION OF THREE-DIMENSIONAL OBJECTS VANTICO INC. 2001-11-13 US disclosed
US-6043323-A LOW VISCOSITY PHOTOCURABLE COMPOSITIONS WHICH, WHEN FULLY CURED, GIVE MOULDED ARTICLES OF EXCELLENT FLEXIBILITY. CIBA SPECIALTY CHEMICALS CORP. (US) 2000-03-28 US disclosed
EP-0554215-B1 Diacrylates and dimethacrylates CIBA GEIGY AG (CH) 1997-01-02 EP disclosed
EP-0596125-A1 CONDENSED THIOPHENE COMPOUND AND PHARMACEUTICAL USE THEREOF YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) 1994-05-11 EP disclosed
EP-0554215-A2 Diacrylates and dimethacrylates CIBA-GEIGY AG (CH) 1993-08-04 EP disclosed
EP-0334378-B1 ADHESIVE COMPOSITIONS MINISTERO DELL' UNIVERSITA' E DELLA RICERCA SCIENTIFICA E TECNOLOGICA (IT) 1993-05-19 EP disclosed
US-4894399-A Light-stabilized polymer microparticles containing epoxy groups CIBA-GEIGY CORPORATION (US) 1990-01-16 US disclosed
US-4880859-A GROUP TRANSFER POLYMERIZATION, COATINGS CIBA-GEIGY CORPORATION (US) 1989-11-14 US disclosed