Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 10/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | UBE2N | P61088 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | APAF1 | O14727 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | RAD52 | P43351 | 1/20 | 0.37 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 5/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7942231 | 0.87 | VDR (0.40) | VDRMAPK1NPSR1SMN1; SMN2MEN1 | |
| SCHEMBL7954066 | 0.86 | MAPK1 (0.52) | VDRMAPK1NPSR1SMN1; SMN2MEN1 | |
| SCHEMBL7942235 | 0.85 | VDR (0.40) | VDRMAPK1NPSR1SMN1; SMN2MEN1 | |
| SCHEMBL9355926 | 0.84 | MAPK1 (0.39) | VDRMAPK1NPSR1SMN1; SMN2MEN1 | |
| SCHEMBL7952163 | 0.77 | NPC1 (0.50) | MAPTRAB9ANPC1 | |
| SCHEMBL8579692 | 0.76 | VDR (0.44) | VDRMAPK1NPSR1SMN1; SMN2MEN1 | |
| SCHEMBL7950327 | 0.74 | TP53 (0.40) | NPSR1SMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL11265812 | 0.73 | MAPK1 (0.55) | VDRMAPK1NPSR1SMN1; SMN2MEN1 | |
| SCHEMBL7954064 | 0.73 | MAPK1 (0.51) | VDRMAPK1NPSR1SMN1; SMN2MEN1 | |
| SCHEMBL4091307 | 0.73 | MAPK1 (0.55) | VDRMAPK1NPSR1SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6231804-B1 | USED FOR HOLLOW CONTAINERS, A FILM, A SHEET, A PIPE, FIBER AND MOLDING;A BLEND OF HIGH MOLECULAR WEIGHT POLYETHYLENE COPOLYMER,AN OLEFIN HOMO OR COPLYMER | CHISSO CORPORATION (JP) | 2001-05-15 | — | — | US | disclosed |