SCHEMBL7950327

SCHEMBL7950327

Cc1ccc(OP(O)F)c(C)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
ACHE P22303 1/20 0.39
L3MBTL1 Q9Y468 4/20 0.36
SMN1; SMN2 Q16637 3/20 0.36
KMT2A Q03164 2/20 0.36
MEN1 O00255 1/20 0.36
HPGD P15428 2/20 0.36
MRGPRX4 Q96LA9 1/20 0.36
CYP3A4 P08684 2/20 0.35
ALDH1A1 P00352 1/20 0.35
NPC1 O15118 1/20 0.35
NFKB1 P19838 1/20 0.35
RAB9A P51151 1/20 0.35
NFKB2 Q00653 1/20 0.35
RELA Q04206 1/20 0.35
LMNA P02545 2/20 0.35
MAPT P10636 2/20 0.35
S1PR4 O95977 1/20 0.35
GAA P10253 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8385833 0.83 TP53 (0.43) TP53TDP1ACHEL3MBTL1SMN1; SMN2
SCHEMBL7950326 0.83 ACHE (0.41) TP53TDP1ACHEL3MBTL1SMN1; SMN2
SCHEMBL3872825 0.83 TP53 (0.43) TP53TDP1ACHEL3MBTL1SMN1; SMN2
SCHEMBL16786357 0.82 TP53 (0.41) TP53TDP1ACHEL3MBTL1SMN1; SMN2
SCHEMBL7950329 0.81 TP53 (0.38) TP53TDP1ACHEL3MBTL1SMN1; SMN2
SCHEMBL20798533 0.80 TP53 (0.40) TP53TDP1ACHEL3MBTL1SMN1; SMN2
SCHEMBL470419 0.79 ACHE (0.44) TP53TDP1ACHEL3MBTL1SMN1; SMN2
SCHEMBL7948553 0.78 SMN1; SMN2 (0.38) TP53ACHEL3MBTL1SMN1; SMN2KMT2A
SCHEMBL17792449 0.77 ACHE (0.43) TP53TDP1ACHEL3MBTL1SMN1; SMN2
SCHEMBL10413289 0.76 ACHE (0.39) TP53TDP1ACHEL3MBTL1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20010004657-A1 OLEFIN(CO-) POLYMER COMPOSITIONS AND METHOD FOR PRODUCING THE SAME ANDCATALYST FOR OLEFIN (CO-) POLYMERIZATION AND METHOD FOR PRODUCING THE SAME CHISSO CORPORATION (JP) 2001-06-21 US disclosed
US-6231804-B1 USED FOR HOLLOW CONTAINERS, A FILM, A SHEET, A PIPE, FIBER AND MOLDING;A BLEND OF HIGH MOLECULAR WEIGHT POLYETHYLENE COPOLYMER,AN OLEFIN HOMO OR COPLYMER CHISSO CORPORATION (JP) 2001-05-15 US disclosed
EP-0972800-A1 MODIFIED OLEFIN (CO)POLYMER COMPOSITION, PROCESS FOR PREPARING THE SAME, AND MODIFIED OLEFIN (CO)POLYMER COMPOSITION MOLDING CHISSO CORPORATION (JP) 2000-01-19 EP disclosed