Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 3/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | SOD1 | P00441 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | STAT1 | P42224 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28357573 | 0.85 | CYP3A4 (0.44) | CYP3A4CYP2C9CYP2C19ACHEHDAC8 | |
| SCHEMBL9460334 | 0.85 | CYP3A4 (0.44) | CYP3A4CYP2C9CYP2C19ACHEHDAC8 | |
| SCHEMBL7942255 | 0.85 | CYP3A4 (0.44) | CYP3A4CYP2C9CYP2C19ACHEHDAC8 | |
| SCHEMBL30403445 | 0.85 | CYP3A4 (0.44) | CYP3A4CYP2C9CYP2C19ACHEHDAC8 | |
| SCHEMBL7942262 | 0.83 | CYP3A4 (0.40) | CYP3A4CYP2C9CYP2C19ACHEHDAC8 | |
| SCHEMBL561428 | 0.81 | CYP3A4 (0.46) | CYP3A4CYP2C9CYP2C19ACHEHDAC8 | |
| SCHEMBL28399919 | 0.78 | ACHE (0.50) | ACHEHDAC8HDAC4HDAC2LMNA | |
| SCHEMBL28401898 | 0.78 | ACHE (0.50) | ACHEHDAC8HDAC4HDAC2LMNA | |
| SCHEMBL12746697 | 0.78 | CYP3A4 (0.44) | CYP3A4CYP2C9CYP2C19ACHEHDAC8 | |
| SCHEMBL102298 | 0.76 | KIF11 (0.49) | CYP3A4CYP2C9CYP2C19ACHEHDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6231804-B1 | USED FOR HOLLOW CONTAINERS, A FILM, A SHEET, A PIPE, FIBER AND MOLDING;A BLEND OF HIGH MOLECULAR WEIGHT POLYETHYLENE COPOLYMER,AN OLEFIN HOMO OR COPLYMER | CHISSO CORPORATION (JP) | 2001-05-15 | — | — | US | disclosed |
| EP-0972800-A1 | MODIFIED OLEFIN (CO)POLYMER COMPOSITION, PROCESS FOR PREPARING THE SAME, AND MODIFIED OLEFIN (CO)POLYMER COMPOSITION MOLDING | CHISSO CORPORATION (JP) | 2000-01-19 | — | — | EP | disclosed |