SCHEMBL7942347

SCHEMBL7942347

CCOc1c(C(C)(C)C)cc(CCCC(=O)OCCO)cc1C(C)(C)C

nearest known ligand 0.40

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 6/20 0.40
VCAM1 P19320 3/20 0.39
MGLL Q99685 1/20 0.39
CNR1 P21554 6/20 0.37
CYP4F2 P78329 1/20 0.37
CYP4A11 Q02928 1/20 0.37
BRD4 O60885 1/20 0.36
DGKA P23743 1/20 0.36
ALOX5 P09917 1/20 0.35
GAA P10253 2/20 0.34
KMT2A Q03164 1/20 0.34
CYP4Z1 Q86W10 1/20 0.34
CYP4F11 Q9HBI6 1/20 0.34
CYP4F12 Q9HCS2 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7940177 0.94 VCAM1 (0.40) CNR2VCAM1CNR1CYP4F2CYP4A11
SCHEMBL7940376 0.93 CNR2 (0.37) CNR2VCAM1MGLLCNR1CYP4F2
SCHEMBL7940366 0.93 VCAM1 (0.41) CNR2VCAM1CNR1CYP4F2CYP4A11
SCHEMBL7933690 0.92 CYP4F2 (0.44) CNR2VCAM1MGLLCYP4F2CYP4A11
SCHEMBL7933682 0.88 CYP4F2 (0.43) CNR2VCAM1CYP4F2CYP4A11BRD4
SCHEMBL7933900 0.87 VCAM1 (0.38) CNR2VCAM1CNR1CYP4F2CYP4A11
SCHEMBL7944826 0.87 VCAM1 (0.40) CNR2VCAM1MGLLDGKAALOX5
SCHEMBL7943173 0.86 CYP4F2 (0.42) CNR2VCAM1CNR1CYP4F2CYP4A11
SCHEMBL7944732 0.86 VCAM1 (0.39) CNR2VCAM1CNR1CYP4F2CYP4A11
SCHEMBL7940450 0.85 CYP4F2 (0.44) VCAM1CYP4F2CYP4A11ALOX5GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6242514-B1 CYCLIC PHOSPHATE OR PHOSPHONATE; HEAT AND OXIDATION STABILIZER ESPECIALLY FOR OLEFIN POLYMERS AND ENGINEERING THERMOPLASTICS SUMITOMO CHEMICAL COMPANY, LTD. (JP) 2001-06-05 US disclosed
US-5914361-A IMPART HEAT STABILITY TO ORGANIC MATERIALS, INCLUDING POLYOLEFINS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-06-22 US disclosed
US-5891939-A POLYMER STABILIZERS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-04-06 US disclosed