SCHEMBL7933682

SCHEMBL7933682

CCOc1c(C(C)(C)C)cc(CCC(=O)OCCCO)cc1C(C)(C)C

nearest known ligand 0.43

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CYP4F2 P78329 1/20 0.43
CYP4A11 Q02928 1/20 0.43
VCAM1 P19320 3/20 0.39
GAA P10253 3/20 0.37
KMT2A Q03164 2/20 0.37
TDP1 Q9NUW8 1/20 0.37
POLB P06746 1/20 0.36
CNR2 P34972 1/20 0.35
APP P05067 1/20 0.35
ALOX5 P09917 1/20 0.35
THRA P10827 1/20 0.34
THRB P10828 1/20 0.34
F2R P25116 1/20 0.34
BRD4 O60885 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7943173 0.96 CYP4F2 (0.42) CYP4F2CYP4A11VCAM1GAAKMT2A
SCHEMBL7940177 0.94 VCAM1 (0.40) CYP4F2CYP4A11VCAM1TDP1POLB
SCHEMBL7933661 0.93 CYP4F2 (0.42) CYP4F2CYP4A11VCAM1GAAKMT2A
SCHEMBL7933690 0.92 CYP4F2 (0.44) CYP4F2CYP4A11VCAM1GAAKMT2A
SCHEMBL7940366 0.90 VCAM1 (0.41) CYP4F2CYP4A11VCAM1TDP1POLB
SCHEMBL7942347 0.88 CNR2 (0.40) CYP4F2CYP4A11VCAM1GAAKMT2A
SCHEMBL7933900 0.87 VCAM1 (0.38) CYP4F2CYP4A11VCAM1TDP1POLB
SCHEMBL8430285 0.87 POLB (0.38) VCAM1GAAPOLBTHRATHRB
SCHEMBL7940008 0.87 ALOX5 (0.41) CYP4F2CYP4A11VCAM1GAAKMT2A
SCHEMBL7940450 0.85 CYP4F2 (0.44) CYP4F2CYP4A11VCAM1GAAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6242514-B1 CYCLIC PHOSPHATE OR PHOSPHONATE; HEAT AND OXIDATION STABILIZER ESPECIALLY FOR OLEFIN POLYMERS AND ENGINEERING THERMOPLASTICS SUMITOMO CHEMICAL COMPANY, LTD. (JP) 2001-06-05 US disclosed
US-5914361-A IMPART HEAT STABILITY TO ORGANIC MATERIALS, INCLUDING POLYOLEFINS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-06-22 US disclosed
US-5891939-A POLYMER STABILIZERS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-04-06 US disclosed