Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | TOP2A | P11388 | 1/20 | 0.42 |
| ▸ | BRAF | P15056 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7945108 | 0.75 | TP53 (0.50) | TP53LMNAALDH1A1KDM4EHSD17B10 | |
| SCHEMBL21753246 | 0.73 | MAPK1 (0.46) | ALDH1A1KDM4EHTT | |
| SCHEMBL27917939 | 0.73 | TAS1R3 (0.39) | LMNAKDM4EHDAC6SMN1; SMN2 | |
| SCHEMBL2088176 | 0.72 | KMT2A (0.56) | LMNAMAOBALDH1A1KDM4EHSD17B10 | |
| SCHEMBL31133349 | 0.72 | MGAM (0.50) | ALDH1A1KDM4EHSD17B10GAAHPGD | |
| SCHEMBL20037664 | 0.72 | ALDH1A1 (0.57) | ALDH1A1KDM4EHPGDUSP2HDAC4 | |
| SCHEMBL12302076 | 0.72 | KDM4E (0.67) | ALDH1A1KDM4EHPGDHDAC1HDAC6 | |
| SCHEMBL30046741 | 0.71 | ALDH1A1 (0.73) | LMNAALDH1A1KDM4EHSD17B10GLA | |
| SCHEMBL7941919 | 0.71 | TP53 (0.42) | TP53LMNAMAOBALDH1A1KDM4E | |
| SCHEMBL21531028 | 0.70 | EPHX2 (0.58) | ALDH1A1KDM4EHPGDHDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010054278-A2 | COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISORDERS | SCHERING CORPORATION (US) | 2010-05-14 | — | — | WO | disclosed |