Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.49 |
| ▸ | GSR | P00390 | 2/20 | 0.47 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.37 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TYR | P14679 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8399034 | 0.86 | KMT2A (0.51) | KMT2ACYP2D6CYP2C9CYP1A2GSR | |
| SCHEMBL7942924 | 0.81 | GSR (0.62) | KMT2ACYP2D6CYP2C9CYP1A2GSR | |
| SCHEMBL7940306 | 0.81 | KMT2A (0.46) | KMT2ACYP2D6CYP2C9CYP1A2GSR | |
| SCHEMBL7942257 | 0.79 | GSR (0.69) | KMT2ACYP2D6CYP2C9CYP1A2GSR | |
| SCHEMBL7940282 | 0.78 | ALDH1A1 (0.51) | KMT2ACYP2D6CYP2C9CYP1A2GSR | |
| SCHEMBL6567754 | 0.78 | HSPA5 (0.44) | CYP2D6CYP2C9HSPA5CYP2C19HIF1A | |
| SCHEMBL7942370 | 0.77 | GSR (0.61) | KMT2ACYP2D6CYP2C9CYP1A2GSR | |
| SCHEMBL6568685 | 0.77 | HSPA5 (0.42) | CYP2D6CYP2C9HSPA5CYP2C19HIF1A | |
| SCHEMBL7940191 | 0.75 | HSPA5 (0.41) | CYP2D6CYP2C9HSPA5CYP2C19HIF1A | |
| SCHEMBL14999492 | 0.75 | HSPA5 (0.46) | CYP2D6CYP2C9HSPA5CYP2C19HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242514-B1 | CYCLIC PHOSPHATE OR PHOSPHONATE; HEAT AND OXIDATION STABILIZER ESPECIALLY FOR OLEFIN POLYMERS AND ENGINEERING THERMOPLASTICS | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 2001-06-05 | — | — | US | disclosed |
| US-5914361-A | IMPART HEAT STABILITY TO ORGANIC MATERIALS, INCLUDING POLYOLEFINS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-06-22 | — | — | US | disclosed |