Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 8/20 | 0.42 |
| ▸ | RARB | P10826 | 7/20 | 0.39 |
| ▸ | RARG | P13631 | 7/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | RXRG | P48443 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.37 |
| ▸ | EIF4A3 | P38919 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.36 |
| ▸ | MLKL | Q8NB16 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7622962 | 0.85 | RARA (0.42) | RARARARBRARGRXRARXRB | |
| SCHEMBL7622996 | 0.85 | CSNK2A2 (0.46) | RARARARBRARGRXRARXRB | |
| SCHEMBL7625435 | 0.85 | RARA (0.44) | RARARARBRARGESR1ESR2 | |
| SCHEMBL7628029 | 0.83 | RARA (0.45) | RARARARBRARGRXRARXRB | |
| SCHEMBL7620448 | 0.83 | RARA (0.39) | RARARARBRARGESR1ESR2 | |
| SCHEMBL7626515 | 0.83 | RXRA (0.44) | RARARARBRARGRXRAKDM4E | |
| SCHEMBL7621362 | 0.83 | RXRA (0.44) | RARARARBRARGRXRARXRB | |
| SCHEMBL7625464 | 0.81 | RARA (0.44) | RARARARBRARGRXRARXRB | |
| SCHEMBL7617704 | 0.80 | RARA (0.46) | RARARARBRARGRXRARXRB | |
| SCHEMBL7628810 | 0.79 | RARA (0.54) | RARARARBRARGRXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6258811-B1 | ADMINISTERING RETINOIC ACID RECEPTOR AGONIST | EISAI CO., LTD. (JP) | 2001-07-10 | — | — | US | disclosed |