Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | SHBG | P04278 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 7/20 | 0.45 |
| ▸ | IDH1 | O75874 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | AR | P10275 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27728893 | 0.91 | CYP3A4 (0.46) | CYP3A4HIF1ACYP2C9ALDH1A1ALOX15 | |
| SCHEMBL200257 | 0.90 | SHBG (0.54) | CYP3A4HIF1ACYP2C9ALDH1A1ALOX15 | |
| SCHEMBL6015498 | 0.82 | CYP3A4 (0.51) | CYP3A4HIF1ACYP2C9ALDH1A1ALOX15 | |
| SCHEMBL23703286 | 0.82 | SHBG (0.47) | CYP3A4HIF1ACYP2C9ALDH1A1ALOX15 | |
| SCHEMBL10948417 | 0.81 | CYP3A4 (0.47) | CYP3A4HIF1ACYP2C9ALDH1A1ALOX15 | |
| SCHEMBL17269273 | 0.79 | CYP3A4 (0.46) | CYP3A4HIF1ACYP2C9ALDH1A1ALOX15 | |
| SCHEMBL13096081 | 0.78 | SHBG (0.57) | CYP3A4HIF1ACYP2C9ALDH1A1ALOX15 | |
| SCHEMBL27728975 | 0.78 | CYP3A4 (0.48) | CYP3A4HIF1ACYP2C9ALDH1A1ALOX15 | |
| SCHEMBL11758727 | 0.77 | HSD17B10 (0.47) | CYP3A4HIF1ACYP2C9ALDH1A1ALOX15 | |
| SCHEMBL1129773 | 0.77 | HMGB1 (0.53) | CYP3A4HIF1ACYP2C9ALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242514-B1 | CYCLIC PHOSPHATE OR PHOSPHONATE; HEAT AND OXIDATION STABILIZER ESPECIALLY FOR OLEFIN POLYMERS AND ENGINEERING THERMOPLASTICS | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 2001-06-05 | — | — | US | disclosed |
| WO-1993013089-A1 | MACROCYCLIC POLYETHER CARBOXYLIC ACIDS | URBAN FRANK J (US) | 1993-07-08 | — | — | WO | disclosed |
| US-4935442-A | Tetrahydrofuran-containing macrocyclic polyether carboxylic acids | PFIZER INC. (US) | 1990-06-19 | — | — | US | disclosed |
| US-4876367-A | ANIMAL GROWTH REGULATORS | PFIZER INC. (US) | 1989-10-24 | — | — | US | disclosed |
| US-4777270-A | INCREASE EFFICIENCY OF FEED UTILIZATION IN RUMINANTS | PFIZER INC. (US) | 1988-10-11 | — | — | US | disclosed |
| US-4050945-A | METALLIC COMPOUND REACTANT, CHELATING COMPOUND REACTANT, BINDER | SUZUKI YOSHIO | 1977-09-27 | — | — | US | disclosed |