SCHEMBL7942488

SCHEMBL7942488

COc1c(CCC(=O)OCCO)cccc1C(C)(C)C

nearest known ligand 0.44

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CYP4F2 P78329 3/20 0.42
CYP4A11 Q02928 3/20 0.42
CDYL Q9Y232 1/20 0.39
TDP1 Q9NUW8 1/20 0.38
KDM4E B2RXH2 1/20 0.37
NR1H4 Q96RI1 1/20 0.37
ALDH1A1 P00352 2/20 0.36
ALOX5 P09917 1/20 0.36
GAA P10253 1/20 0.36
NLRP3 Q96P20 1/20 0.35
POLB P06746 1/20 0.34
NTRK1 P04629 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7933896 0.93 CYP4F2 (0.40) CYP4F2CYP4A11CDYLTDP1NR1H4
SCHEMBL7942330 0.88 CYP4F2 (0.46) CYP4F2CYP4A11CDYLTDP1KDM4E
SCHEMBL14874376 0.87 CYP4F2 (0.54) CYP4F2CYP4A11CDYLNR1H4ALDH1A1
SCHEMBL7940022 0.84 CYP4F2 (0.43) CYP4F2CYP4A11CDYLTDP1KDM4E
SCHEMBL8397208 0.81 RARG (0.36) CYP4F2CYP4A11TDP1ALDH1A1ALOX5
SCHEMBL7933984 0.81 ALDH1A1 (0.37) CYP4F2CYP4A11ALDH1A1ALOX5
SCHEMBL7796396 0.81 NR1H4 (0.47) NR1H4POLB
SCHEMBL6565823 0.78 NR1H4 (0.38) TDP1KDM4ENR1H4ALDH1A1ALOX5
SCHEMBL7942652 0.78 KMT2A (0.40) CYP4F2CYP4A11TDP1ALDH1A1ALOX5
SCHEMBL8397561 0.77 ALOX5 (0.43) CYP4F2CYP4A11TDP1ALDH1A1ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6242514-B1 CYCLIC PHOSPHATE OR PHOSPHONATE; HEAT AND OXIDATION STABILIZER ESPECIALLY FOR OLEFIN POLYMERS AND ENGINEERING THERMOPLASTICS SUMITOMO CHEMICAL COMPANY, LTD. (JP) 2001-06-05 US disclosed
US-5914361-A IMPART HEAT STABILITY TO ORGANIC MATERIALS, INCLUDING POLYOLEFINS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-06-22 US disclosed
US-5891939-A POLYMER STABILIZERS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-04-06 US disclosed