⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1276560 | 0.73 | TSHR (0.41) | — | |
| SCHEMBL3314643 | 0.72 | — | — | |
| SCHEMBL28484724 | 0.67 | TSHR (0.30) | — | |
| SCHEMBL437714 | 0.64 | TSHR (0.32) | — | |
| SCHEMBL27554334 | 0.64 | TSHR (0.33) | — | |
| SCHEMBL23581990 | 0.63 | TSHR (0.35) | — | |
| SCHEMBL27301 | 0.63 | TSHR (0.35) | — | |
| SCHEMBL321664 | 0.63 | TSHR (0.35) | — | |
| SCHEMBL5273091 | 0.62 | — | — | |
| Benzene SCHEMBL29078675 | 0.62 | LMNA (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0785233-B1 | Peroxide-cured blends of polyacrylate and partially hydrogenated nitrile rubbers | ZEON CHEMICALS LP (US) | 2001-10-24 | — | — | EP | claimed |
| EP-0785233-A2 | Peroxide-cured blends of polyacrylate and partially hydrogenated nitrile rubbers | Zeon Chemicals Incorporated (US) | 1997-07-23 | — | — | EP | claimed |
| US-5612418-A | HEAT AND OIL RESISTANT, USE IN AUTOMOBILE ENGINES | ZEON CHEMICAL INCORPORATED (US) | 1997-03-18 | — | — | US | claimed |