Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.40 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | TYMS | P04818 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9795832 | 0.84 | ALDH1A1 (0.42) | ALDH1A1HSD17B10CYP2A6TSHRTDP1 | |
| SCHEMBL17743678 | 0.79 | CA1 (0.39) | ALDH1A1HSD17B10CYP2A6TSHRTDP1 | |
| SCHEMBL17503355 | 0.71 | PAX8 (0.37) | ALDH1A1HSD17B10TDP1PAX8HPRT1 | |
| SCHEMBL10262240 | 0.67 | ALDH1A1 (0.46) | ALDH1A1HSD17B10CYP2A6TSHRTDP1 | |
| SCHEMBL6881238 | 0.67 | ALDH1A1 (0.46) | ALDH1A1HSD17B10CYP2A6TSHRTDP1 | |
| SCHEMBL7691627 | 0.67 | ALDH1A1 (0.46) | ALDH1A1HSD17B10CYP2A6TSHRTDP1 | |
| SCHEMBL268735 | 0.65 | ALDH1A1 (0.65) | ALDH1A1HSD17B10CYP2A6TSHRTDP1 | |
| SCHEMBL29391827 | 0.65 | ALDH1A1 (0.65) | ALDH1A1HSD17B10CYP2A6TSHRTDP1 | |
| SCHEMBL30186719 | 0.65 | ALDH1A1 (0.65) | ALDH1A1HSD17B10CYP2A6TSHRTDP1 | |
| SCHEMBL21359837 | 0.65 | MAPT (0.38) | ALDH1A1TDP1KDM4EHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696289-B1 | BENZO[F]QUINOXALINDIONE DERIVATIVES, THEIR PREPARATION AND THEIR USE IN DRUGS | SCHERING AG (DE) | 1997-03-12 | — | — | EP | claimed |
| JP-10130247-A | — | — | None | — | — | JP | disclosed |
| CN-119285640-A | Naphthalene dione pyrazine fused ring compound and preparation method and application thereof | 西京学院 | 2025-01-10 | — | — | CN | disclosed |
| US-6191132-B1 | THERAPY FOR PARKINSON'S DISEASE; SYNERGISTIC MIXTURE WITH ANTIDOPAMINE AGENT | SCHERING AKTIENGESELLSCHAFT (DE) | 2001-02-20 | — | — | US | disclosed |
| US-6057120-A | Redox-active compounds and their use | ROCHE DIAGNOSTICS GMBH (DE) | 2000-05-02 | — | — | US | disclosed |
| CN-1041935-C | Benzo[f]quinoxalindione derivatives, their preparation and their use in drugs | SCHERING AG (DE) | 1999-02-03 | — | — | CN | disclosed |
| JP-H10130247-A | REDOX ACTIVE COMPOUND AND USE THEREOF | BOEHRINGER MANNHEIM GMBH | 1998-05-19 | — | — | JP | disclosed |
| US-5721234-A | TREATING CONVULSIONS, ANXIETY, CEREBRAL HYPOXIA/ISCHEMIA, PARKINSON*S DISEASE | WARNER-LAMBERT COMPANY (US) | 1998-02-24 | — | — | US | disclosed |
| US-5616586-A | Tricyclic quinoxalinediones | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1997-04-01 | — | — | US | disclosed |
| WO-1996017832-A1 | NOVEL GLUTAMATE RECEPTOR ANTAGONISTS: FUSED CYCLOALKYLQUINOXALINEDIONES | WARNER-LAMBERT COMPANY (US) | 1996-06-13 | — | — | WO | disclosed |
| CN-1122136-A | Benzo[f]quinoxalindione derivatives, their preparation and their use in drugs | SCHERING AG (DE) | 1996-05-08 | — | — | CN | disclosed |
| WO-1993008188-A1 | TRICYCLIC QUINOXALINEDIONES AS GLUTAMATE RECEPTOR ANTAGONISTS | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1993-04-29 | — | — | WO | disclosed |