Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 20/20 | 0.77 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2955249 | 0.90 | HTR3A (0.78) | HTR3AKCNH2CYP3A4CYP2C19 | |
| SCHEMBL2959708 | 0.90 | HTR3A (0.78) | HTR3AKCNH2CYP3A4CYP2C19 | |
| SCHEMBL2954830 | 0.89 | HTR3A (0.77) | HTR3AKCNH2CYP3A4CYP2C19 | |
| SCHEMBL7940567 | 0.89 | HTR3A (0.77) | HTR3AKCNH2CYP3A4CYP2C19 | |
| Hydrochloric Acid SCHEMBL2962581 | 0.88 | HTR3A (0.75) | HTR3AKCNH2CYP3A4CYP2C19 | |
| SCHEMBL2961016 | 0.88 | HTR3A (0.74) | HTR3AKCNH2CYP3A4CYP2C19 | |
| SCHEMBL2957247 | 0.87 | HTR3A (1.00) | HTR3AKCNH2CYP3A4CYP2C19 | |
| SCHEMBL5639567 | 0.86 | HTR3A (0.79) | HTR3AKCNH2CYP3A4CYP2C19 | |
| Hydrochloric Acid SCHEMBL2955239 | 0.86 | HTR3A (0.78) | HTR3AKCNH2CYP3A4CYP2C19 | |
| SCHEMBL2956887 | 0.85 | HTR3A (0.70) | HTR3AKCNH2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7781430-B2 | Benzoxazole carboxamides for treating CINV and IBS-D | ALBANY MOLECULAR RESEARCH, INC. (US) | 2010-08-24 | — | — | US | disclosed |
| US-7781430-B2 | Benzoxazole carboxamides for treating CINV and IBS-D | ALBANY MOLECULAR RESEARCH, INC. (US) | 2010-08-24 | — | — | US | disclosed |
| US-20080108609-A1 | Benzoxazole Carboxamides For Treating CINV and IBS-D | AMR TECHNOLOGY, INC. (US) | 2008-05-08 | — | — | US | disclosed |
| US-20080108609-A1 | Benzoxazole Carboxamides For Treating CINV and IBS-D | AMR TECHNOLOGY, INC. (US) | 2008-05-08 | — | — | US | disclosed |
| US-20060183769-A1 | Benzoxazole carboxamides for treating CINV and IBS-D | AMR TECHNOLOGY, INC. (US) | 2006-08-17 | — | — | US | disclosed |
| US-20060183769-A1 | Benzoxazole carboxamides for treating CINV and IBS-D | AMR TECHNOLOGY, INC. (US) | 2006-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080108609-A1 | Benzoxazole Carboxamides For Treating CINV and IBS-D | HTR3E, BRS3, HTR3A | HTR3A 3/4885KCNH2 1078/4885CYP3A4 755/4885 |
| US-20060183769-A1 | Benzoxazole carboxamides for treating CINV and IBS-D | HTR3E, BRS3, HTR3A | HTR3A 3/4885KCNH2 1078/4885CYP3A4 755/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.