Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 5/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 5/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | RXRA | P19793 | 2/20 | 0.33 |
| ▸ | RXRG | P48443 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 2/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7942914 | 1.00 | GAA (0.41) | GAAMEN1KMT2APPARGPPARD | |
| SCHEMBL7942918 | 0.87 | GAA (0.45) | GAAMEN1KMT2APPARGPPARD | |
| SCHEMBL7942916 | 0.87 | GAA (0.45) | GAAMEN1KMT2APPARGPPARD | |
| SCHEMBL7941464 | 0.84 | PPARG (0.38) | PPARGPPARDPPARATAS1R3TAS1R1 | |
| SCHEMBL7941466 | 0.84 | PPARG (0.38) | PPARGPPARDPPARATAS1R3TAS1R1 | |
| SCHEMBL16202071 | 0.83 | PPARG (0.41) | GAAMEN1KMT2APPARGPPARA | |
| SCHEMBL17233213 | 0.77 | MAPT (0.49) | GAAMEN1KMT2APPARGPPARA | |
| SCHEMBL17233347 | 0.74 | ESR1 (0.47) | GAAMEN1KMT2ANPSR1MAPT | |
| SCHEMBL18598370 | 0.72 | ATM (0.61) | GAAKMT2APPARAMAPTL3MBTL1 | |
| SCHEMBL27369627 | 0.72 | ATM (0.61) | GAAKMT2APPARAMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6274586-B1 | SYNERGISTIC MIXTURE WITH METHYL (N-METHOXY)-PHENYLCARBAMATE DERIVATIVE | BASF AKTIENGESELLSCHAFT (DE) | 2001-08-14 | — | — | US | claimed |