Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 6/20 | 0.55 |
| ▸ | THRA | P10827 | 5/20 | 0.41 |
| ▸ | RXRA | P19793 | 5/20 | 0.41 |
| ▸ | RXRB | P28702 | 3/20 | 0.41 |
| ▸ | RXRG | P48443 | 3/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | RARG | P13631 | 1/20 | 0.40 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 4/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | CD69 | Q07108 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7786532 | 0.91 | THRB (0.61) | THRBTHRARXRARXRBRXRG | |
| SCHEMBL7786480 | 0.87 | NR1H4 (0.44) | THRBTHRARXRARXRBRXRG | |
| SCHEMBL7796449 | 0.85 | THRB (0.55) | THRBTHRARXRARXRBRXRG | |
| SCHEMBL7786586 | 0.79 | RXRA (0.51) | THRBRXRARXRBRXRGPPARG | |
| SCHEMBL7795955 | 0.79 | THRB (0.44) | THRBRXRARXRBPPARGRARG | |
| SCHEMBL7796135 | 0.78 | HSPA5 (0.60) | THRBTHRARXRARXRBRXRG | |
| SCHEMBL7792677 | 0.78 | NR1H4 (0.49) | THRBTHRARXRARXRBRXRG | |
| SCHEMBL4009929 | 0.76 | THRB (0.46) | THRBTHRARXRARXRBRXRG | |
| SCHEMBL7792544 | 0.75 | THRB (0.40) | THRBTHRARXRAPPARGRARG | |
| SCHEMBL7796121 | 0.75 | NR1H4 (0.44) | THRBPTGER4CYP1A2CYP2D6SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242514-B1 | CYCLIC PHOSPHATE OR PHOSPHONATE; HEAT AND OXIDATION STABILIZER ESPECIALLY FOR OLEFIN POLYMERS AND ENGINEERING THERMOPLASTICS | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 2001-06-05 | — | — | US | disclosed |
| US-5914361-A | IMPART HEAT STABILITY TO ORGANIC MATERIALS, INCLUDING POLYOLEFINS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-06-22 | — | — | US | disclosed |