SCHEMBL7943145

SCHEMBL7943145

Cc1cc(CCC(=O)OCCO)cc(C2CCCCC2)c1O

nearest known ligand 0.41

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.41
ALDH1A1 P00352 3/20 0.40
CYP4F2 P78329 1/20 0.38
CYP4A11 Q02928 1/20 0.38
APP P05067 2/20 0.36
TDP1 Q9NUW8 1/20 0.35
NUDT1 P36639 1/20 0.35
BACE1 P56817 1/20 0.35
KDM4E B2RXH2 1/20 0.35
MEN1 O00255 1/20 0.35
MAPT P10636 1/20 0.35
KMT2A Q03164 1/20 0.35
PTGDR2 Q9Y5Y4 4/20 0.34
MGLL Q99685 1/20 0.33
THRA P10827 2/20 0.33
THRB P10828 2/20 0.33
HRH3 Q9Y5N1 1/20 0.33
PTGDR Q13258 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10764740 0.92 ALOX5 (0.42) ALOX5ALDH1A1CYP4F2CYP4A11APP
SCHEMBL10351700 0.91 ALOX5 (0.41) ALOX5ALDH1A1APPTDP1NUDT1
SCHEMBL10352435 0.88 ALOX5 (0.40) ALOX5ALDH1A1APPTDP1NUDT1
SCHEMBL10352289 0.87 ALOX5 (0.39) ALOX5ALDH1A1APPTDP1NUDT1
SCHEMBL7944855 0.87 ALOX5 (0.40) ALOX5ALDH1A1CYP4F2CYP4A11APP
SCHEMBL10352290 0.86 ESR1 (0.45) ALOX5ALDH1A1
SCHEMBL7933549 0.86 ALDH1A1 (0.47) ALOX5ALDH1A1CYP4F2CYP4A11MEN1
SCHEMBL4045061 0.86 ALOX5 (0.46) ALOX5ALDH1A1APPTDP1NUDT1
SCHEMBL7933803 0.85 KMT2A (0.42) ALOX5ALDH1A1APPTDP1NUDT1
SCHEMBL10352065 0.85 PTGDR2 (0.43) ALOX5ALDH1A1NUDT1BACE1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6242514-B1 CYCLIC PHOSPHATE OR PHOSPHONATE; HEAT AND OXIDATION STABILIZER ESPECIALLY FOR OLEFIN POLYMERS AND ENGINEERING THERMOPLASTICS SUMITOMO CHEMICAL COMPANY, LTD. (JP) 2001-06-05 US disclosed
US-5914361-A IMPART HEAT STABILITY TO ORGANIC MATERIALS, INCLUDING POLYOLEFINS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-06-22 US disclosed
EP-0861847-A2 Stabilizer composition and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-09-02 EP disclosed