SCHEMBL7943166

SCHEMBL7943166

COc1ccc(COC(C)CO)cc1C(C)(C)C

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.42
GAA P10253 1/20 0.42
ALOX15 P16050 3/20 0.38
CYP3A4 P08684 2/20 0.38
LMNA P02545 1/20 0.38
TP53 P04637 1/20 0.38
HPGD P15428 1/20 0.38
ALOX12 P18054 2/20 0.38
RARA P10276 2/20 0.36
RARB P10826 2/20 0.36
RARG P13631 2/20 0.36
MMP1 P03956 1/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
FOS P01100 1/20 0.35
TTR P02766 1/20 0.35
JUN P05412 1/20 0.35
NR3C1 P04150 1/20 0.35
HSD17B1 P14061 1/20 0.35
HSD17B2 P37059 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8400777 0.86 ALDH1A1 (0.40) ALDH1A1GAAALOX15CYP3A4LMNA
SCHEMBL10204755 0.78 CYP3A4 (0.47) ALDH1A1GAAALOX15CYP3A4LMNA
SCHEMBL9636833 0.78 GAA (0.46) ALDH1A1GAAALOX15CYP3A4LMNA
SCHEMBL25586653 0.78 CYP3A4 (0.60) ALDH1A1GAAALOX15CYP3A4LMNA
SCHEMBL7941404 0.77 ALDH1A1 (0.43) ALDH1A1GAAALOX15CYP3A4LMNA
SCHEMBL7942911 0.76 ALDH1A1 (0.34) ALDH1A1
SCHEMBL6568774 0.75 CYP3A4 (0.44) ALDH1A1GAAALOX15CYP3A4LMNA
SCHEMBL9635394 0.74 GAA (0.43) ALDH1A1GAAALOX15CYP3A4LMNA
SCHEMBL13964102 0.73 LMNA (0.44) ALDH1A1GAAALOX15CYP3A4LMNA
SCHEMBL31588889 0.73 LMNA (0.44) ALDH1A1GAAALOX15CYP3A4LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6242514-B1 CYCLIC PHOSPHATE OR PHOSPHONATE; HEAT AND OXIDATION STABILIZER ESPECIALLY FOR OLEFIN POLYMERS AND ENGINEERING THERMOPLASTICS SUMITOMO CHEMICAL COMPANY, LTD. (JP) 2001-06-05 US disclosed
US-5874494-A DETERIORATION STABILIZER FOR THERMOPLASTIC RESIN; OXIDATION RESISTANCE, DISCOLORATION INHIBITION, HEAT RESISTANCE, CROSSLINKING INHIBITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-02-23 US disclosed