Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 5/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7943067 | 0.82 | NR1H4 (0.48) | ALDH1A1TSHRTDP1L3MBTL1TP53 | |
| SCHEMBL7944820 | 0.80 | ALDH1A1 (0.43) | ALDH1A1TSHRTDP1L3MBTL1TP53 | |
| SCHEMBL11553487 | 0.79 | TDP1 (0.56) | CA2ALDH1A1TSHRTDP1L3MBTL1 | |
| SCHEMBL28465355 | 0.79 | CA2 (0.55) | CA2ALDH1A1TSHRGABRA1GABRB2 | |
| SCHEMBL7941411 | 0.78 | NR5A2 (0.49) | CA2ALDH1A1TSHRCYP3A4MAPK1 | |
| SCHEMBL7942933 | 0.78 | SMN1; SMN2 (0.49) | CA2ALDH1A1MAPK1LMNAHSD17B10 | |
| SCHEMBL28348492 | 0.78 | CA2 (0.53) | CA2ALDH1A1TSHRGABRA1GABRB2 | |
| SCHEMBL7940022 | 0.74 | CYP4F2 (0.43) | CA2ALDH1A1GABRA1GABRB2TDP1 | |
| SCHEMBL36533 | 0.74 | ALDH1A1 (0.67) | ALDH1A1TSHRTDP1L3MBTL1TP53 | |
| SCHEMBL7940297 | 0.74 | CA2 (0.48) | CA2ALDH1A1TSHRGABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242514-B1 | CYCLIC PHOSPHATE OR PHOSPHONATE; HEAT AND OXIDATION STABILIZER ESPECIALLY FOR OLEFIN POLYMERS AND ENGINEERING THERMOPLASTICS | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 2001-06-05 | — | — | US | disclosed |
| US-5914361-A | IMPART HEAT STABILITY TO ORGANIC MATERIALS, INCLUDING POLYOLEFINS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-06-22 | — | — | US | disclosed |