Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.32 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7106552 | 0.88 | — | — | |
| SCHEMBL7941171 | 0.83 | CYP19A1 (0.32) | MAPTKMT2AMEN1CYP19A1NPC1 | |
| SCHEMBL7945466 | 0.83 | GAA (0.33) | MAPTKMT2AALDH1A1HPGDMEN1 | |
| SCHEMBL8160847 | 0.81 | GAA (0.36) | MAPTKMT2AALDH1A1HPGDMEN1 | |
| SCHEMBL6904389 | 0.80 | ALDH1A1 (0.33) | ALDH1A1CYP19A1NPC1RAB9ALMNA | |
| SCHEMBL8823139 | 0.71 | MAPT (0.35) | MAPTKMT2AALDH1A1HPGDMEN1 | |
| Hydrochloric Acid SCHEMBL8823180 | 0.70 | MAPT (0.33) | MAPTKMT2AALDH1A1HPGDMEN1 | |
| SCHEMBL16424180 | 0.69 | ALDH1A1 (0.38) | MAPTKMT2AALDH1A1HPGDMEN1 | |
| SCHEMBL7934592 | 0.69 | — | — | |
| SCHEMBL16338953 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6316558-B1 | POLYMERIZING OLEFIN USING CATALYST COMPRISING TRANSITION METAL COMPOUND, COMPOUND CAPABLE OF A REACTING WITH TRANSITION METAL COMPOUND TO FORM A CATIONIC TRANSITION METAL COMPOUND, ORGANOMETALLIC TO FORM POLYOLEFIN | TOSOH CORPORATION (JP) | 2001-11-13 | — | — | US | disclosed |