Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | PDE5A | O76074 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7106552 | 0.87 | — | — | |
| SCHEMBL6904389 | 0.86 | ALDH1A1 (0.33) | CYP19A1LMNANPC1RAB9A | |
| SCHEMBL7943339 | 0.83 | MAPT (0.34) | CYP19A1SMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL19056250 | 0.81 | — | — | |
| SCHEMBL17698557 | 0.79 | LMNA (0.32) | SMN1; SMN2TSHRPDE5ANPSR1MEN1 | |
| SCHEMBL17698585 | 0.79 | NPSR1 (0.33) | SMN1; SMN2NPSR1MEN1KMT2ALMNA | |
| SCHEMBL6902276 | 0.74 | CNR2 (0.30) | — | |
| SCHEMBL17698610 | 0.73 | TSHR (0.31) | SMN1; SMN2TSHR | |
| SCHEMBL17698583 | 0.73 | ESR1 (0.34) | — | |
| SCHEMBL5076771 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6316558-B1 | POLYMERIZING OLEFIN USING CATALYST COMPRISING TRANSITION METAL COMPOUND, COMPOUND CAPABLE OF A REACTING WITH TRANSITION METAL COMPOUND TO FORM A CATIONIC TRANSITION METAL COMPOUND, ORGANOMETALLIC TO FORM POLYOLEFIN | TOSOH CORPORATION (JP) | 2001-11-13 | — | — | US | disclosed |