Chelidamic Acid

Chelidamic Acid

SCHEMBL794359

O=C(O)c1cc(O)cc(C(=O)O)n1.[Tb]

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 2/20 0.61
TSHR P16473 2/20 0.61
HIF1A Q16665 1/20 0.61
TDP1 Q9NUW8 2/20 0.50
KDM4E B2RXH2 2/20 0.50
ACMSD Q8TDX5 1/20 0.50
CA12 O43570 1/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
CA7 P43166 1/20 0.46
CA9 Q16790 1/20 0.46
CA14 Q9ULX7 1/20 0.46
HCAR2 Q8TDS4 6/20 0.41
DAO P14920 1/20 0.41
LMNA P02545 1/20 0.41
ALDH1A1 P00352 2/20 0.39
GPR35 Q9HC97 1/20 0.38
HCAR1 Q9BXC0 3/20 0.38
CYTH3 O43739 1/20 0.38
BTK Q06187 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Chelidamic Acid SCHEMBL743778 0.97 ALOX15 (0.64) ALOX15TSHRHIF1ATDP1KDM4E
Chelidamic Acid SCHEMBL113302 0.95 ALOX15 (0.61) ALOX15TSHRHIF1ATDP1KDM4E
Chelidamic Acid SCHEMBL31146805 0.95 ALOX15 (0.61) ALOX15TSHRHIF1ATDP1KDM4E
SCHEMBL11381523 0.85 ALOX15 (0.50) ALOX15TSHRHIF1ATDP1KDM4E
SCHEMBL1999536 0.81 CA12 (0.48) ALOX15TSHRHIF1ATDP1KDM4E
SCHEMBL6509907 0.78 ALOX15 (0.67) ALOX15TSHRHIF1ATDP1KDM4E
SCHEMBL8213827 0.77 MLLT1 (0.43) ALOX15TSHRHIF1AHCAR2ALDH1A1
SCHEMBL12161238 0.77 CYP1A2 (0.56) ALOX15TSHRHIF1ATDP1KDM4E
SCHEMBL2705265 0.76 ALOX15 (0.56) ALOX15TSHRHIF1ATDP1KDM4E
SCHEMBL336311 0.76 TSHR (1.00) ALOX15TSHRHIF1ATDP1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2615938-A1 TAMPERPROOF CASE SICPA HOLDING SA (CH) 2013-07-24 EP disclosed
WO-2012035145-A1 TAMPERPROOF CASE SICPA HOLDING SA (CH) 2012-03-22 WO disclosed